Johnston James, George Michael, Karkos Petros D, Dwivedi Rhagav C, Leong Samuel C
Department of Otolaryngology, Queen Alexandra Hospital, Southwick Hill Road, Portsmouth, UK.
Ecancermedicalscience. 2013 Mar 21;7:298. doi: 10.3332/ecancer.2013.298. Print 2013.
Breast cancer can very rarely result in late metastases to the paranasal sinuses.
We present a 75-year-old woman who developed sinonasal symptoms mimicking sinusitis 20 years after receiving a breast cancer diagnosis. Rigid nasendoscopy was unremarkable, but due to persistent unilateral nasal symptoms and suspicious radiological findings, the patient underwent endoscopic biopsies of macroscopically normal sinuses which confirmed metastatic breast cancer.
High suspicion index, a thorough history, and examination are of paramount importance as metastases to the sinuses from breast cancer can occur even 20 years after diagnosis.
乳腺癌极少会导致晚期转移至鼻窦。
我们报告一名75岁女性,在被诊断为乳腺癌20年后出现类似鼻窦炎的鼻窦症状。硬性鼻内镜检查未见明显异常,但由于持续的单侧鼻部症状及可疑的影像学表现,患者接受了对宏观上正常鼻窦的内镜活检,结果证实为转移性乳腺癌。
高度的怀疑指数、详尽的病史及检查至关重要,因为乳腺癌转移至鼻窦甚至可在诊断后20年发生。