Weizman Z, Vardi O, Binsztok M
Pediatric Gastroenterology and Nutrition Service, Soroka Medical Center, Beer-Sheva, Israel.
J Pediatr Gastroenterol Nutr. 1990 May;10(4):451-3. doi: 10.1097/00005176-199005000-00006.
Fingerprints were obtained from 46 patients with celiac disease and compared with those of 46 control subjects matched for sex and ethnic origin. Whorls were more frequent and ulnar loops were less frequent, significantly, in celiac patients than in controls. A digital pattern of four or more whorls was present in 69% of celiac patients, but in only 28% of controls (p less than 0.001). As a diagnostic test, the fingerprint's sensitivity, specificity, and positive and negative predictive values were 66, 73, 67, and 71%, respectively. Similarly, a pattern of four or less ulnar loops was evident in 44% of celiac patients as opposed to only 19% of controls (p less than 0.005). Sensitivity, specificity, and positive and negative predictive values were 46%, 81%, 62%, and 63%, respectively. We conclude that particular dermatoglyphic patterns are significantly more common in patients with celiac disease than in controls. We therefore suggest that this marker be used as a diagnostic clue, indicating the need for further investigation.
从46例乳糜泻患者获取指纹，并与46名性别和种族匹配的对照受试者的指纹进行比较。与对照组相比，乳糜泻患者的斗型纹更常见，而尺侧箕型纹则明显较少见。69%的乳糜泻患者有四个或更多斗型纹的指嵴纹型，但对照组中只有28%有（p<0.001）。作为一种诊断测试，指纹的敏感性、特异性、阳性预测值和阴性预测值分别为66%、73%、67%和71%。同样，44%的乳糜泻患者有四个或更少尺侧箕型纹的明显指嵴纹型，而对照组中只有19%有（p<0.005）。敏感性、特异性、阳性预测值和阴性预测值分别为46%、81%、62%和63%。我们得出结论，特定的皮纹模式在乳糜泻患者中比在对照组中明显更常见。因此，我们建议将该标志物用作诊断线索，提示需要进一步检查。
