Institut für Genetik, Universität zu Köln, Köln, Germany.
PLoS One. 2013 Apr 8;8(4):e60123. doi: 10.1371/journal.pone.0060123. Print 2013.
The coalescent with recombination is a fundamental model to describe the genealogical history of DNA sequence samples from recombining organisms. Considering recombination as a process which acts along genomes and which creates sequence segments with shared ancestry, we study the influence of single recombination events upon tree characteristics of the coalescent. We focus on properties such as tree height and tree balance and quantify analytically the changes in these quantities incurred by recombination in terms of probability distributions. We find that changes in tree topology are often relatively mild under conditions of neutral evolution, while changes in tree height are on average quite large. Our results add to a quantitative understanding of the spatial coalescent and provide the neutral reference to which the impact by other evolutionary scenarios, for instance tree distortion by selective sweeps, can be compared.
有重组的合并是描述来自重组生物的 DNA 序列样本的系统发生历史的基本模型。考虑重组为沿着基因组起作用的过程，该过程创建具有共同祖先的序列片段，我们研究了单个重组事件对合并树特征的影响。我们专注于树高和树平衡等属性，并以概率分布的形式分析重组引起的这些数量的变化。我们发现，在中性进化的条件下，树拓扑结构的变化通常相对温和，而树高的变化平均相当大。我们的结果增加了对空间合并的定量理解，并为其他进化情景（例如选择清扫引起的树变形）的影响提供了中性参考。
