Shirouzu K, Isomoto H, Kajiwara K, Kakegawa T, Morimatsu M
First Department of Surgery, Kurume University School of Medicine, Japan.
Nihon Geka Gakkai Zasshi. 1990 Mar;91(3):373-85.
Metachronous liver metastasis developed less than in 5% of v0 and v1 groups, while it developed in 22% of v2 and v3 groups. In addition, it developed in 15% of EF(I) group, in 19% of EF group, in 10% of Intramural greater than Extramural group and in 16% of the Intramural less than or equal to Extramural group. Six-year survival rate of v0, v1, v2 and v3 groups in the cases of curative resection for advanced colo-rectal cancer were 97%, 85%, 57% and 51%, respectively. Also those of E, EF, EI(F), Intramural, Intramural greater than Extramural and Intramural less than or equal to Extramural groups were 83%, 65%, 55%, 86%, 80% and 55%, respectively. Non-hematogenous recurrence developed in 19.4% of v3 group, in 13.6% of EF(I) group and in 15% of Intramural less than or equal to Extramural group. Conclusions were as follows: (1) There was a close relationship between venous invasion and development of liver metastasis (or of non-hematogenous recurrence) and survival of patients. (2) It was proved that the diagnostic criteria of venous invasion established by the authors were good indices to predict survival of colo-rectal cancer patients.
异时性肝转移在v0组和v1组中的发生率低于5%，而在v2组和v3组中的发生率为22%。此外，在EF(I)组中的发生率为15%，在EF组中的发生率为19%，在壁内大于壁外组中的发生率为10%，在壁内小于或等于壁外组中的发生率为16%。晚期结直肠癌根治性切除病例中，v0、v1、v2和v3组的6年生存率分别为97%、85%、57%和51%。同样，E组、EF组、EI(F)组、壁内组、壁内大于壁外组和壁内小于或等于壁外组的6年生存率分别为83%、65%、55%、86%、80%和55%。非血行转移在v3组中的发生率为19.4%，在EF(I)组中的发生率为13.6%，在壁内小于或等于壁外组中的发生率为15%。结论如下：(1)静脉侵犯与肝转移（或非血行转移）的发生以及患者的生存之间存在密切关系。(2)作者建立的静脉侵犯诊断标准被证明是预测结直肠癌患者生存的良好指标。
