KHLim, Limburg Catholic University College, PHL University College, dpt.PHL-Healthcare Research, Hasselt, Leuven, Belgium.
Obes Facts. 2013;6(2):152-64. doi: 10.1159/000346315. Epub 2013 Apr 12.
The psychological health in obese women during pregnancy has been poorly studied.
To compare levels of anxiety and depressed mood during pregnancy in obese versus normal-weight women.
63 obese pregnant women and 156 normal-weight controls were included prospectively before 15 weeks of gestation. Levels of state and trait anxiety and depressed mood were measured during the first, second and third trimester of pregnancy. A linear mixed-effect model with repeated measures was used to evaluate group differences.
The levels of state anxiety significantly increased from trimester 1 to trimester 3 in obese pregnant women (beta = 3.70; p = 0.007), while this parameter remained constant throughout pregnancy in normal-weight women. Levels of trait anxiety and depressed mood significantly decreased from trimester 1 to trimester 2 in controls, but not in obese pregnant women. Variables such as maternal education, ethnicity, marital state, psychological history and miscarriages, parity and smoking behaviour had significant effects on anxiety and/or depressed moods during pregnancy. Obese pregnant women show higher levels of anxiety and depressive symptomatology compared to normal-weight pregnant women.
Interventional programmes aiming at preventing the deleterious influence of maternal obesity on perinatal outcomes should include a psycho-educational program specifically tailored to this high-risk group.
肥胖女性在孕期的心理健康状况尚未得到充分研究。
比较肥胖孕妇与正常体重孕妇在孕期的焦虑和抑郁情绪水平。
前瞻性纳入 63 名肥胖孕妇和 156 名正常体重对照组，在妊娠 15 周前进行研究。在妊娠的第一、第二和第三孕期测量状态和特质焦虑及抑郁情绪水平。采用重复测量线性混合效应模型评估组间差异。
肥胖孕妇的状态焦虑水平从孕期 1 期到 3 期显著增加（β=3.70；p=0.007），而正常体重孕妇的这一参数在整个孕期保持不变。对照组的特质焦虑和抑郁情绪水平从孕期 1 期到 2 期显著下降，但肥胖孕妇没有下降。母亲教育、种族、婚姻状况、心理史和流产史、产次和吸烟行为等变量对孕期的焦虑和/或抑郁情绪有显著影响。与正常体重孕妇相比，肥胖孕妇表现出更高水平的焦虑和抑郁症状。
旨在预防母体肥胖对围产期结局的不良影响的干预性方案应包括针对这一高危人群的特定心理教育方案。
