嗜酸性细胞性内翻性乳头状瘤：33例经鼻内镜手术的临床行为及结果
Oncocytic Schneiderian papillomas: Clinical behavior and outcomes of the endoscopic endonasal approach in 33 cases.
作者信息
Karligkiotis Apostolos, Bignami Maurizio, Terranova Paola, Gallo Stefania, Meloni Francesco, Padoan Giovanni, Lombardi Davide, Nicolai Piero, Castelnuovo Paolo
机构信息
Department of Otorhinolaryngology, University of Sassari, Sassari, Italy.
出版信息
Head Neck. 2014 May;36(5):624-30. doi: 10.1002/hed.23341. Epub 2013 Jul 2.
BACKGROUND
The purpose of this study was to evaluate the clinical behavior of oncocytic Schneiderian papillomas in relation to the rate of malignant transformation and recurrences and to report the long-term results of the endoscopic endonasal treatment.
METHODS
A retrospective analysis was carried out on patients with oncocytic papilloma, endoscopically managed over the past 20 years, at 2 university centers following a uniform policy.
RESULTS
Thirty-three patients were treated between November 1991 and December 2010. The mean follow-up period was 62 months. We observed 2 cases of persistence (6%) at the maxillary sinus level. Both of these patients underwent endoscopic surgical revision. Squamous cell carcinoma (SCC) was observed in 1 patient (3%).
CONCLUSION
The endonasal endoscopic technique proved to be a safe and effective approach for the treatment of oncocytic papillomas. An oncocytic papilloma is not to be considered a negative prognostic factor in terms of malignant transformation or recurrence.
背景
本研究的目的是评估嗜酸性细胞性施耐德乳头状瘤的临床行为与恶性转化和复发率的关系，并报告鼻内镜下治疗的长期结果。
方法
对过去20年在2个大学中心按照统一策略进行内镜治疗的嗜酸性细胞乳头状瘤患者进行回顾性分析。
结果
1991年11月至2010年12月期间共治疗了33例患者。平均随访期为62个月。我们观察到2例上颌窦水平持续性病变（6%）。这2例患者均接受了鼻内镜手术修正。1例患者（3%）发生了鳞状细胞癌（SCC）。
结论
鼻内镜技术被证明是治疗嗜酸性细胞乳头状瘤的一种安全有效的方法。嗜酸性细胞乳头状瘤在恶性转化或复发方面不应被视为不良预后因素。
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