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颞动脉炎:采用新方案改善患者评估

Temporal arteritis: improving patient evaluation with a new protocol.

作者信息

Alberts Michael

出版信息

Perm J. 2013 Winter;17(1):56-62. doi: 10.7812/TPP/12-067.

Abstract

CONTEXT

The process of diagnosing temporal arteritis remains controversial. Although temporal artery biopsy has long been the standard tool of evaluation, its poor sensitivity has prompted investigation of other methods to aid in diagnosis. Improved clinical evaluation and various imaging techniques have been suggested as ways to establish the diagnosis through noninvasive means and to improve biopsy yield.

OBJECTIVE

To retrospectively report and evaluate the process and experience of the Kaiser Permanente Northwest Region in implementing a new protocol that includes an enhanced clinical evaluation as well as the incorporation of color duplex ultrasonography in addition to biopsy when appropriate for temporal arteritis evaluation.

RESULTS

A 38% reduction in the number of temporal artery biopsies performed was achieved through the new protocol, which was created by a multidisciplinary process, including stakeholders from all departments involved. The percentage of abnormal biopsy results rose from 8.5% at baseline to 24%. No cases of the disease were missed after careful evaluation of clinical and medical-legal records.

CONCLUSIONS

Adding specialist clinical evaluation and color duplex ultrasonography to the standard diagnostic workup for temporal arteritis creates a rapid, noninvasive, resource-sensible means to diagnose giant cell arteritis, to improve temporal artery biopsy yield, and to decrease the total number of biopsies done. The diagnosis can be made in some cases by clinical evaluation and color duplex ultrasonography alone, thereby saving the patient an unnecessary surgical procedure. Protocols such as this can be implemented by multidisciplinary cooperation in a patient-centered, integrated system.

摘要

背景

颞动脉炎的诊断过程仍存在争议。尽管颞动脉活检长期以来一直是评估的标准工具,但其低敏感性促使人们研究其他辅助诊断方法。改善临床评估和各种成像技术已被提议作为通过非侵入性手段进行诊断并提高活检阳性率的方法。

目的

回顾性报告并评估凯撒永久医疗集团西北地区实施一项新方案的过程和经验,该方案包括强化临床评估,并在适用于颞动脉炎评估时除活检外还纳入彩色双功超声检查。

结果

通过新方案,颞动脉活检的数量减少了38%,该方案是通过多学科过程制定的,包括所有相关部门的利益相关者。活检异常结果的百分比从基线时的8.5%上升到24%。在仔细评估临床和医疗法律记录后,没有漏诊该疾病的病例。

结论

在颞动脉炎的标准诊断检查中增加专科临床评估和彩色双功超声检查,可创造一种快速、非侵入性、资源合理的手段来诊断巨细胞动脉炎,提高颞动脉活检阳性率,并减少活检总数。在某些情况下,仅通过临床评估和彩色双功超声检查即可做出诊断,从而为患者省去不必要的手术。这样的方案可以通过以患者为中心的综合系统中的多学科合作来实施。

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