Ni Xuefeng, Wu Ping, Wu Changping, Wu Jianfeng, Ji Mei, Gu Xiaofang, Tian Bo
Departments of Oncology, The Third Affiliated Hospital, Soochow University, Changzhou, Jiangsu 213003;
Oncol Lett. 2013 Apr;5(4):1129-1132. doi: 10.3892/ol.2013.1183. Epub 2013 Feb 6.
The present study discusses a patient with C1 vertebral metastasis from adenocarcinoma of the left lung. The patient was a 31-year-old female suffering from neck pain who was referred by her physician. Magnetic resonance imaging revealed osteolytic destruction of the C1 vertebra. Chest and computed tomographic scans revealed lung carcinoma changes involving the left lung. A biopsy confirmed adenocarcinoma of the left lung. Abnormal activity was present in the cervical spine (C1) region in a radionuclide bone scan. The patient was then referred to an oncologist. The spine was stabilized with a rigid collar and a course of radiation therapy and pain medication was initiated immediately. At the 9-month follow-up examination, there was no evidence of progression on the MRI scans and the main neck symptoms had disappeared. At present, the overall survival (OS) time is 11 months. Patients complaining of new onset back or neck pain should be assumed to have vertebral metastasis until proven otherwise. Trivial trauma should be taken seriously in these cases and investigated with appropriate clinical, laboratory and imaging examinations.
本研究讨论了一名患有左肺腺癌C1椎体转移的患者。该患者为一名31岁女性,因颈部疼痛由其医生转诊而来。磁共振成像显示C1椎体溶骨性破坏。胸部和计算机断层扫描显示左肺有肺癌改变。活检证实为左肺腺癌。放射性核素骨扫描显示颈椎(C1)区域有异常活动。该患者随后被转诊至肿瘤学家处。使用硬颈托稳定脊柱,并立即开始进行放射治疗和给予止痛药物。在9个月的随访检查中,MRI扫描没有进展的迹象,主要颈部症状已消失。目前,总生存(OS)时间为11个月。在未得到其他证实之前,应假定主诉新发背部或颈部疼痛的患者患有椎体转移。在这些病例中,轻微创伤应予以重视,并通过适当的临床、实验室和影像学检查进行排查。