Department of Diagnostic Pathology, Tsurumi University School of Dental Medicine, Yokohama, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 May;115(5):646-51. doi: 10.1016/j.oooo.2013.01.023.
Adenomatoid odontogenic tumor (AOT) is not a new entity and has long been a subject of fascination after a century of recorded observation because of its unique biological profile. Hundreds of publications have covered a variety of aspects, ranging from demographic data to clinicopathologic features to treatment modalities. It is widely acknowledged that the first detailed reports of AOT were initially published in 1915 by Harbitz in Norway and later in 1916 by Wohl in the United States. However, it is very likely that earlier textbook and journal descriptions of AOT exist. This prompted us to review the extensive world literature on AOT dating back to the early part of the 19th century. Here we present a revised historical perspective of AOT, with a view to closing gaps in earlier knowledge about this entity and also encouraging further research.
腺牙源性肿瘤（AOT）并不是一个新的实体，在经过一个世纪的有记录观察后，由于其独特的生物学特征，它一直是人们关注的焦点。数百篇出版物涵盖了从人口统计学数据到临床病理特征再到治疗方式的各种方面。人们普遍认为，AOT 的首次详细报告最初是由挪威的 Harbitz 于 1915 年首次发表的，随后美国的 Wohl 于 1916 年也发表了相关报告。然而，很可能在这之前的教科书和期刊中就已经有关于 AOT 的描述了。这促使我们回顾了可追溯到 19 世纪早期的关于 AOT 的广泛世界文献。在这里，我们呈现了一个经过修订的 AOT 历史视角，旨在弥合对这一实体早期认识的差距，并鼓励进一步的研究。
