Asavapiriyanont Suvanna, Lolekha Rangsima, Roongpisuthipong Anuvat, Wiratchai Amornpan, Kaoiean Surasak, Suksripanich Orapin, Chalermchockcharoenkit Amphan, Ausavapipit Jaruensook, Srifeungfung Somporn, Pattanasin Sarika, Katz Kenneth A
BMC Public Health. 2013 Apr 22;13:373. doi: 10.1186/1471-2458-13-373.
Data on sexually transmitted infections (STI) prevalence among HIV-infected women in Thailand are limited. We studied, among HIV-infected women, prevalence of STI symptoms and signs; prevalence and correlates of having any STI; prevalence and correlates of Chlamydia trachomatis (CT) or Neisseria gonorrhoeae (GC) among women without CT and/or GC symptoms or signs; and number of women without CT and/or GC symptoms or signs needed to screen (NNS) to detect one woman with CT and/or GC overall, among pregnant women, and among women ≤25 years.
During October 2004-September 2006, HIV-infected women at 3 obstetrics and gynecology clinics were asked about sexual behaviors and STI symptoms, physically examined, and screened for chlamydia, gonorrhea, trichomoniasis, and syphilis. Multivariate logistic regression was used to identify correlates of infections. NNS was calculated using standard methods.
Among 1,124 women, 526 (47.0%) had STI symptoms or signs, 469 (41.7%) had CT and/or GC symptoms or signs, and 133 (11.8%) had an STI. Correlates of having an STI included pregnancy and having STI signs. Among 469 women and 655 women with vs. without CT and/or GC symptoms or signs, respectively, 43 (9.2%) vs. 31 (4.7%), 2 (0.4%) vs. 9 (1.4%), and 45 (9.6%) vs. 38 (5.8%) had CT, GC, or "CT or GC", respectively; correlates included receiving care at university hospitals and having sex with a casual partner within 3 months. NNS for women overall and women ≤25 years old were 18 (95% CI, 13-25) and 11 (95% CI, 6-23), respectively; and for pregnant and non-pregnant women, 8 (95% CI, 4-24) and 19 (95% CI, 14-27), respectively.
STI prevalence among HIV-infected women, including CT and GC among those without symptoms or signs, was substantial. Screening for CT and GC, particularly for pregnant women, should be considered.
泰国感染艾滋病毒女性中性传播感染（STI）患病率的数据有限。我们研究了感染艾滋病毒女性中性传播感染症状和体征的患病率；任何性传播感染的患病率及其相关因素；无症状或体征的女性中沙眼衣原体（CT）或淋病奈瑟菌（GC）的患病率及其相关因素；以及在总体、孕妇和25岁及以下女性中，筛查出一名患有CT和/或GC的女性所需的无症状或体征的女性数量（NNS）。
在2004年10月至2006年9月期间，对3家妇产科诊所中感染艾滋病毒的女性询问性行为和性传播感染症状，进行体格检查，并筛查衣原体、淋病、滴虫病和梅毒。采用多因素逻辑回归分析确定感染的相关因素。使用标准方法计算NNS。
在1124名女性中，526名（47.0%）有性传播感染症状或体征，469名（41.7%）有CT和/或GC症状或体征，133名（11.8%）患有性传播感染。性传播感染的相关因素包括怀孕和有性传播感染体征。在分别有和没有CT和/或GC症状或体征的469名和655名女性中，分别有43名（9.2%）和31名（4.7%）、2名（0.4%）和9名（1.4%）、45名（9.6%）和38名（5.8%）患有CT、GC或“CT或GC”；相关因素包括在大学医院接受治疗以及在3个月内与临时伴侣发生性行为。总体女性和25岁及以下女性的NNS分别为18（95%CI，13 - 25）和11（95%CI，6 - 23）；孕妇和非孕妇的NNS分别为8（95%CI，4 - 24）和19（95%CI，14 - 27）。
感染艾滋病毒女性中性传播感染的患病率很高，包括无症状或体征者中的CT和GC感染。应考虑对CT和GC进行筛查，尤其是对孕妇。
