Topchiev Institute of Petrochemical Synthesis RAS, Moscow, Russia.
Anal Chim Acta. 2013 May 2;775:25-40. doi: 10.1016/j.aca.2013.02.039. Epub 2013 Mar 7.
Monolithic columns invented in chromatographic praxis almost 40 years ago gained nowadays a lot of popularity in separations by liquid chromatographic technique. At the same time, application of monolithic columns in gas chromatography is less common and only a single review published by Svec et al. covers this field of research. Since that time a lot of new findings on application and properties of monolithic columns in gas chromatography have been published in the literature deserving consideration and discussion. This review considers preparation of monolithic columns for GC, an impact of preparation conditions on column performance, optimization of separation conditions for GC analysis on monolithic columns and other important aspects of preparation and usage of monolithic capillary columns in GC. A final part of the review discusses the modern trends and possible applications in the future of capillary monolithic columns in GC.
大约 40 年前在色谱实践中发明的整体柱，如今在液相色谱技术的分离中获得了广泛的关注。与此同时，整体柱在气相色谱中的应用则相对较少，仅有 Svec 等人发表的一篇综述涵盖了该研究领域。此后，大量关于气相色谱中整体柱的应用和性能的新发现已在文献中发表，值得考虑和讨论。本文综述了用于 GC 的整体柱的制备、制备条件对柱性能的影响、在整体柱上进行 GC 分析时分离条件的优化以及 GC 中整体毛细管柱的制备和使用的其他重要方面。综述的最后一部分讨论了毛细管整体柱在 GC 中的现代趋势和未来可能的应用。
