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Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation.

作者信息

Yin Lichen, Song Ziyuan, Qu Qiuhao, Kim Kyung Hoon, Zheng Nan, Yao Catherine, Chaudhury Isthier, Tang Haoyu, Gabrielson Nathan P, Uckun Fatih M, Cheng Jianjun

机构信息

Department of Materials Science and Engineering, University of Illinois, Urbana-Champaign, 1304 West Green Street, Urbana, IL 61801, USA.

出版信息

Angew Chem Int Ed Engl. 2013 May 27;52(22):5757-61. doi: 10.1002/anie.201209991. Epub 2013 Apr 22.

DOI:10.1002/anie.201209991
PMID:23610013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3800743/
Abstract
摘要

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本文引用的文献

1
A bioreducible polymer for efficient delivery of Fas-silencing siRNA into stem cell spheroids and enhanced therapeutic angiogenesis.一种可还原的聚合物,可有效将 Fas 沉默 siRNA 递送至干细胞球体,并增强治疗性血管生成。
Angew Chem Int Ed Engl. 2012 Nov 19;51(47):11899-903. doi: 10.1002/anie.201206595. Epub 2012 Oct 16.
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Multifunctional hybrid nanoconjugates for efficient in vivo delivery of immunomodulating oligonucleotides and enhanced antitumor immunity.用于免疫调节寡核苷酸高效体内递送及增强抗肿瘤免疫力的多功能杂化纳米缀合物。
Angew Chem Int Ed Engl. 2012 Sep 17;51(38):9670-3. doi: 10.1002/anie.201204989. Epub 2012 Aug 22.
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Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.最大限度地提高 siRNA 脂质纳米粒在体内肝脏基因沉默中的效力。
Angew Chem Int Ed Engl. 2012 Aug 20;51(34):8529-33. doi: 10.1002/anie.201203263. Epub 2012 Jul 10.
4
Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment.用于癌症治疗中系统性 siRNA 递送的肿瘤归巢聚硅氧烷/乙二醇壳聚糖自交联纳米粒。
Angew Chem Int Ed Engl. 2012 Jul 16;51(29):7203-7. doi: 10.1002/anie.201201390. Epub 2012 Jun 13.
5
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.分子自组装核酸纳米颗粒用于靶向体内 siRNA 递送。
Nat Nanotechnol. 2012 Jun 3;7(6):389-93. doi: 10.1038/nnano.2012.73.
6
Self-assembled RNA interference microsponges for efficient siRNA delivery.自组装 RNA 干扰微海绵用于高效 siRNA 递送。
Nat Mater. 2012 Feb 26;11(4):316-22. doi: 10.1038/nmat3253.
7
Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models.不同胃肠道上皮细胞共培养模型中纳米颗粒转染的比较研究。
J Control Release. 2012 May 30;160(1):48-56. doi: 10.1016/j.jconrel.2012.01.041. Epub 2012 Feb 3.
8
Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation.超声响应性和甘露糖修饰脂质体有效抑制鼠细胞间黏附分子-1,从而抑制急性肝炎症。
Hepatology. 2012 Jul;56(1):259-69. doi: 10.1002/hep.25607. Epub 2012 Jun 6.
9
Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers.聚合物纳米粒的口服给药:胃肠道黏液屏障。
Adv Drug Deliv Rev. 2012 May 1;64(6):557-70. doi: 10.1016/j.addr.2011.12.009. Epub 2011 Dec 24.
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Reactive and bioactive cationic α-helical polypeptide template for nonviral gene delivery.用于非病毒基因传递的反应性和生物活性阳离子α-螺旋多肽模板。
Angew Chem Int Ed Engl. 2012 Jan 27;51(5):1143-7. doi: 10.1002/anie.201104262. Epub 2011 Dec 7.