Department of Oriental Medical Food and Nutrition, Semyung University, Jecheon 390-711, Korea.
Nutr Res Pract. 2013 Apr;7(2):139-45. doi: 10.4162/nrp.2013.7.2.139. Epub 2013 Apr 1.
There is a lack of data on metabolic risk factors during pre-puberty, which is important for identifying the subgroups of youth, at whom early interventions should be targeted. In this study, we evaluated the prevalence of metabolic risk factors and its subsequent relations with dietary patterns in Korean pre-pubertal children through a cross-sectional sample (n = 1,008; boys = 513) of pre-pubertal children (aged 8-9 years) from a sub-study of the Korea Metabolic Syndrome Research Initiatives (KMSRI) in Seoul, Korea. Measures of anthropometry and blood pressure as well as fasting blood samples were used in the analysis. A three-day food records were collected. The metabolic syndrome was defined according to the age-adjusted National Cholesterol Education Program Adult Treatment Panel III guidelines. An added metabolic risk score was calculated for each subject by summing the quintile values of the five individual risk factors. Among the 5 risk components of metabolic syndrome, high waist circumference (WC) was the major factor (P < 0.001). A significant increasing trend of the added metabolic syndrome risk score was observed with the increase of WC (P (trend) < 0.001) among both genders. The cutoff point for high WC for pre-pubertal children was 61.3 cm for boys and 59.9 cm for girls. The prevalence of high triglyceride (TG) values was significantly higher in girls than it was in boys (P < 0.01). Girls in the highest quintile of balanced dietary pattern scores had lower TG values (P (trend) = 0.032) than did those in the lowest quintile. Moreover, girls in the highest quintile of western dietary pattern scores showed increasing trend for the added metabolic risk score (P (trend) = 0.026) compared with those in the lowest quintile. Adverse associations exist between western dietary patterns and the accumulation of metabolic risks among girls, not in boys, even during pre-puberty.
青春期前儿童的代谢危险因素数据缺乏，这对于确定应将早期干预针对的青年亚组很重要。在这项研究中，我们通过横断面样本（n = 1008；男孩= 513）评估了韩国青春期前儿童（年龄为 8-9 岁）的代谢危险因素的流行情况及其与饮食模式的后续关系，该样本来自韩国首尔的韩国代谢综合征研究倡议（KMSRI）的子研究。分析中使用了人体测量和血压测量以及空腹血样。收集了三天的食物记录。代谢综合征根据年龄调整的国家胆固醇教育计划成人治疗小组 III 指南来定义。为每个受试者计算了一个附加的代谢风险评分，方法是将五个单独风险因素的五分位值相加。在代谢综合征的 5 个风险成分中，高腰围（WC）是主要因素（P < 0.001）。在两性中，随着 WC 的增加，附加代谢综合征风险评分呈显著增加趋势（P（趋势）< 0.001）。青春期前儿童高 WC 的临界点为男孩 61.3 厘米，女孩 59.9 厘米。女孩的高甘油三酯（TG）值的患病率明显高于男孩（P < 0.01）。平衡饮食模式评分最高五分位的女孩的 TG 值较低（P（趋势）= 0.032）比最低五分位的女孩。此外，与最低五分位相比，西方饮食模式评分最高五分位的女孩的附加代谢风险评分呈上升趋势（P（趋势）= 0.026）。即使在青春期前，西方饮食模式与女孩代谢风险的积累之间也存在不良关联，而不是男孩。
