Department of Medicine, University of California-San Francisco, San Francisco VA Medical Center, San Francisco, California 94121, USA.
J Ren Nutr. 2013 May;23(3):207-9. doi: 10.1053/j.jrn.2013.02.005.
Most kidney transplantation programs have a maximum body mass index (BMI) above which they will not place a patient on the active waiting list. However, obesity is common among patients with end-stage renal disease (ESRD), and weight loss is difficult, resulting in many patients being denied the opportunity to be considered for a transplant. BMI limits are in place because of data that outcomes are worse among obese transplant recipients than among those with lower BMI. However, the data to suggest that patient and graft survival are affected by obesity are not consistent, and obese patients with ESRD have better survival after kidney transplantation compared with remaining on dialysis. Therefore, it is important to carefully examine the question of BMI limits to ensure that we are achieving the right balance and making the best use of donated kidneys.
大多数肾脏移植项目都有一个最大的体重指数 (BMI) 限制,超出这个限制,他们将不会将患者列入活跃的候补名单。然而,终末期肾病 (ESRD) 患者中肥胖症很常见,而且减肥很困难,导致许多患者被拒绝考虑进行移植。BMI 限制的存在是因为有数据表明,肥胖的移植受者的预后比 BMI 较低的受者差。然而,关于肥胖是否会影响患者和移植物的生存的数据并不一致,而且与继续透析相比,患有 ESRD 的肥胖患者在接受肾脏移植后的生存率更高。因此,仔细研究 BMI 限制的问题以确保我们达到了正确的平衡并充分利用捐赠的肾脏非常重要。