Nanda Arti, Alshalfan Faisal, Al-Otaibi Mohammad, Al-Sabah Humoud, Rajy Jihan M
Pediatric Dermatology Unit, As'ad Al-Hamad Dermatology Center, Kuwait.
Am J Dermatopathol. 2013 Jun;35(4):503-6. doi: 10.1097/DAD.0b013e3182770626.
Febrile ulceronecrotic Mucha-Habermann disease is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta, characterized by a rapidly progressive course with predominant ulceronecrotic lesions associated with fever and systemic manifestations. It carries a great morbidity and is potentially fatal. The exact pathogenesis is not clear, and it has been proposed to be the result of hypersensitivity reaction to an infection. We report a patient with febrile ulceronecrotic Mucha-Habermann disease in a 12-year-old boy in whom the condition was most likely precipitated by parvovirus infection, and he showed a favorable response to a combination of prednisolone with narrow band ultraviolet B (NB-UVB) phototherapy.
发热性溃疡性坏死性穆查-哈伯曼病是急性痘疮样苔藓样糠疹的一种罕见暴发型，其特征为病程快速进展，主要为溃疡性坏死性损害，并伴有发热和全身表现。它具有很高的发病率，且有潜在致命性。确切发病机制尚不清楚，有人提出它是对感染的超敏反应所致。我们报告一例12岁男孩患发热性溃疡性坏死性穆查-哈伯曼病，该疾病很可能由细小病毒感染诱发，且他对泼尼松龙联合窄谱中波紫外线（NB-UVB）光疗表现出良好反应。
