Department of Dermatology, K. E. M. Hospital, Pune, Maharashtra, India.
Indian J Dermatol Venereol Leprol. 2019 Nov-Dec;85(6):660-663. doi: 10.4103/ijdvl.IJDVL_552_17.
Febrile ulceronecrotic Mucha-Habermann disease is a very rare and severe variant of pityriasis lichenoides et varioliformis acuta. Adult cases are difficult to diagnose as in the early course they can mimic erythema multiforme or lymphomatoid papulosis. We report a case of a 38-year-old woman who presented with 90% body surface area involvement, fever, diarrhea, malaise and associated comorbidities. She was treated with systemic steroids and methotrexate but suffered a fatal outcome. So far, a total of 65 cases are reported in the literature.
发热性溃疡性坏死性蕈样肉芽肿病是一种非常罕见且严重的急性 pityriasis lichenoides et varioliformis acuta 变体。成人病例难以诊断，因为在早期阶段，它们可能类似于多形红斑或淋巴瘤样丘疹病。我们报告了一例 38 岁女性病例，她的体表面积受累达 90%，伴有发热、腹泻、乏力和相关合并症。她接受了全身类固醇和甲氨蝶呤治疗，但最终结果是致命的。迄今为止，文献中总共报告了 65 例病例。
