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粘红酵母性角膜炎:一种来自印度东部的罕见真菌。

Rhodotorula mucilaginosa Keratitis: a rare fungus from Eastern India.

作者信息

Saha Suman, Sengupta Jayangshu, Chatterjee Debapriya, Banerjee Debdulal

机构信息

Ocular Microbiology Laboratory Services, Priyamvada Birla Aravind Eye Hospital, 10 Loudon Street, Kolkata; Department of Microbiology, Vidyasagar University, Midnapore, India.

出版信息

Indian J Ophthalmol. 2014 Mar;62(3):341-4. doi: 10.4103/0301-4738.111133.

DOI:10.4103/0301-4738.111133
PMID:23619486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4061676/
Abstract

Rhodotorula mucilaginosa rarely cause keratitis in immunocompromised individuals. A 30 year old male with history of minor trauma presented with cotton wool like stromal infiltration and hypopyon in left eye. Microbiological examination of corneal scraping showed fungal hyphae and yeast cells in direct smear. Molecular identification of the organism was performed which showed 100% homology with Rhodotorula mucilaginosa. Management of these cases is difficult often necessitating surgical procedures. However further reports are necessary to understand the disease and establish a treatment protocol.

摘要

粘红酵母在免疫功能低下个体中很少引起角膜炎。一名有轻微外伤史的30岁男性左眼出现棉絮样基质浸润和前房积脓。角膜刮片的微生物学检查在直接涂片上显示有真菌菌丝和酵母细胞。对该生物体进行了分子鉴定,结果显示与粘红酵母有100%的同源性。这些病例的治疗很困难,常常需要手术治疗。然而,需要更多的报告来了解这种疾病并建立治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/f99c15488060/IJO-62-341-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/d6893b404f60/IJO-62-341-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/5025abbb0296/IJO-62-341-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/530a0ba8821f/IJO-62-341-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/240999ff5b2d/IJO-62-341-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/cb31deb6f137/IJO-62-341-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/f99c15488060/IJO-62-341-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/d6893b404f60/IJO-62-341-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/5025abbb0296/IJO-62-341-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/530a0ba8821f/IJO-62-341-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/240999ff5b2d/IJO-62-341-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/cb31deb6f137/IJO-62-341-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d5/4061676/f99c15488060/IJO-62-341-g006.jpg

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本文引用的文献

1
Rhodotorula infection. A systematic review of 128 cases from literature.红酵母感染。对文献中128例病例的系统评价。
Rev Iberoam Micol. 2008 Sep 30;25(3):135-40. doi: 10.1016/s1130-1406(08)70032-9.
2
Healthcare-associated fungal infections: beyond Candida and Aspergillus.医疗保健相关真菌感染:超越念珠菌和曲霉菌
South Med J. 2007 Feb;100(2):130-1. doi: 10.1097/SMJ.0b013e31802ed1ab.
3
Rhodotorula rubra keratitis and melting after repeated penetrating keratoplasty.反复穿透性角膜移植术后红酵母性角膜炎及角膜溶解
真菌性角膜炎:增长趋势及常见决定因素研究
Nepal J Epidemiol. 2017 Jun 30;7(2):685-693. doi: 10.3126/nje.v7i2.17975. eCollection 2017 Jun.
4
Rhodotorula keratitis: a rarely encountered ocular pathogen.红酵母角膜炎:一种罕见的眼部病原体。
Case Rep Ophthalmol. 2014 Oct 2;5(3):302-10. doi: 10.1159/000365986. eCollection 2014 Sep.
Eur J Ophthalmol. 2005 Jan-Feb;15(1):135-7. doi: 10.1177/112067210501500123.
4
Risk of fungemia due to Rhodotorula and antifungal susceptibility testing of Rhodotorula isolates.红酵母引起真菌血症的风险及红酵母分离株的抗真菌药敏试验
J Clin Microbiol. 2003 Nov;41(11):5233-5. doi: 10.1128/JCM.41.11.5233-5235.2003.
5
Rhodotorula infection in a corneal graft following penetrating keratoplasty.穿透性角膜移植术后角膜移植片中的红酵母感染。
Can J Ophthalmol. 2003 Apr;38(3):225-7. doi: 10.1016/s0008-4182(03)80065-0.
6
Rhodotorula rubra endophthalmitis in an HIV positive patient.一名HIV阳性患者发生深红酵母性眼内炎。
Br J Ophthalmol. 2002 Dec;86(12):1444-5. doi: 10.1136/bjo.86.12.1444.
7
Rhodotorula sp. infection in corneal interface following lamellar keratoplasty--a case report.板层角膜移植术后角膜界面的红酵母感染——病例报告
Acta Ophthalmol Scand. 1999 Apr;77(2):227-8. doi: 10.1034/j.1600-0420.1999.770223.x.
8
In vitro activity of the new triazole voriconazole (UK-109,496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens.新型三唑类药物伏立康唑(UK-109,496)对机会性丝状真菌和双相真菌以及常见和新出现的酵母病原体的体外活性。
J Clin Microbiol. 1998 Jan;36(1):198-202. doi: 10.1128/JCM.36.1.198-202.1998.
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New and emerging yeast pathogens.新型及新兴酵母病原体
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Rhodotorula causing chronic dacryocystitis: a case report.红酵母引起慢性泪囊炎:一例报告
Indian J Ophthalmol. 1995 Dec;43(4):196-8.