Karakter Child and Adolescent Psychiatry, P.O. Box 40244, 8004 DE, Zwolle, The Netherlands.
J Autism Dev Disord. 2013 Dec;43(12):2793-806. doi: 10.1007/s10803-013-1825-8.
Different views on the origin of deficits in action chaining in autism spectrum disorders (ASD) have been posited, ranging from functional impairments in action planning to internal models supporting motor control. Thirty-one children and adolescents with ASD and twenty-nine matched controls participated in a two-choice reach-to-grasp paradigm wherein participants received cueing information indicating either the object location or the required manner of grasping. A similar advantage for location cueing over grip cueing was found in both groups. Both accuracy and reaction times of the ASD group were indistinguishable from the control group. In contrast, movement times of the ASD group were significantly delayed in comparison with controls. These findings suggest that movement execution rather than action planning is deficient in ASD, and that deficits in action chaining derive from impairments in internal action models supporting action execution.
关于自闭症谱系障碍（ASD）中动作连锁缺陷的起源，存在不同的观点，从动作规划的功能障碍到支持运动控制的内部模型都有涉及。31 名 ASD 儿童和青少年和 29 名匹配的对照组参与者参加了一个二选一的伸手抓握范式，参与者收到提示信息，提示的内容是物体位置或所需的抓握方式。在这两个组中都发现了位置提示比握把提示更有优势。ASD 组的准确性和反应时间与对照组没有区别。相比之下，ASD 组的运动时间与对照组相比明显延迟。这些发现表明，运动执行而不是动作规划存在缺陷，动作连锁的缺陷源于支持动作执行的内部动作模型的损伤。
