Department of General Surgery, East Kent Hospitals University NHS Foundation Trust, Kent, UK.
Front Med. 2013 Jun;7(2):264-9. doi: 10.1007/s11684-013-0259-1. Epub 2013 Apr 26.
The effect of the severity of appendiceal inflammation on post-operative stay in children following appendicectomy has shown conflicting results. This study was conducted to determine the association between the severity of appendiceal inflammation and post-operative stay amongst children undergoing open appendicectomy. A retrospective cohort study was conducted at a District General Hospital for two years. A total of 204 patients were included in the study with an age range between 3 and 16 years. Females were 54.9% while the rest were male. Mean age was 12.5 ± 3 years. The association of the severity of appendiceal inflammation and post-operative stay was assessed by multivariable Cox Proportional hazards model. Mean post-operative stay was 2.32 days (95% CI 2.14-2.51). Macroscopically perforated appendix, histological inflammation and post-operative complications were significantly associated with post-operative stay on univariable analysis (P < 0.05). Whereas, the multivariable analysis showed that the post-operative stay was significantly prolonged only in case of either perforated appendix or post-operative complications while it remained unaffected by the histological inflammation.
阑尾炎症的严重程度对儿童阑尾切除术后的住院时间有影响,但结果存在矛盾。本研究旨在确定儿童开腹阑尾切除术后阑尾炎症严重程度与术后住院时间之间的关系。在一家地区综合医院进行了一项为期两年的回顾性队列研究。共纳入 204 例年龄在 3 至 16 岁之间的患者。女性占 54.9%,其余为男性。平均年龄为 12.5 ± 3 岁。通过多变量 Cox 比例风险模型评估阑尾炎症严重程度与术后住院时间的关系。术后平均住院时间为 2.32 天(95%CI 2.14-2.51)。单变量分析显示,宏观上穿孔的阑尾、组织学炎症和术后并发症与术后住院时间显著相关(P < 0.05)。而多变量分析显示,只有在阑尾穿孔或术后并发症的情况下,术后住院时间才显著延长,而组织学炎症对其无影响。