Institute of Medical Informatics, University of Münster, Münster.
Bioinformatics. 2013 Jul 1;29(13):1679-81. doi: 10.1093/bioinformatics/btt198. Epub 2013 Apr 25.
RSVSim is a tool for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. The structural variations can be generated randomly, based on user-supplied genomic coordinates or associated to various kinds of repeats. The package further comprises functions to estimate the distribution of structural variation sizes from real datasets.
RSVSim is implemented in R and available at http://www.bioconductor.org. A vignette with detailed descriptions of the functions and examples is included.
RSVSim 是一个工具，用于模拟任何作为 FASTA 文件或 R 中的数据包提供的基因组中的缺失、插入、倒位、串联重复和易位。结构变异可以根据用户提供的基因组坐标或与各种重复相关而随机生成。该软件包还包括从实际数据集估计结构变异大小分布的功能。
RSVSim 是用 R 编写的，可在 http://www.bioconductor.org 上获得。其中包含一个带有功能和示例详细说明的简介。
