Kostenko L Kh, Rozantsev E G, Ozhogina O A
Izv Akad Nauk SSSR Biol. 1990 Mar-Apr(2):305-8.
Different types of active inhibitors of the reaction of nitrite hemoglobin oxidation have been revealed and studied. The dependence of inhibition of methemoglobin formation, on concentration of inhibitors at pH 5.9 and 7.17 has been determined. Differential absorption spectra of the inhibitors in the presence sodium nitrite in UV and visual light has been studied. The values of oxidation-reduction potentials have been estimated. Possible mechanism of action of the inhibitors has been discussed.
已发现并研究了亚硝酸盐血红蛋白氧化反应的不同类型活性抑制剂。测定了在pH值为5.9和7.17时,高铁血红蛋白形成的抑制作用对抑制剂浓度的依赖性。研究了在亚硝酸钠存在下,抑制剂在紫外光和可见光区域的差分吸收光谱。估算了氧化还原电位值。讨论了抑制剂可能的作用机制。