Roland J, Dobbeleir A, Vandevivere J, Ham H R
Department of Nuclear Medicine, A.Z. Middelheim, Antwerp, Belgium.
Nucl Med Commun. 1990 Apr;11(4):319-26. doi: 10.1097/00006231-199004000-00011.
Radionuclide gastric emptying studies are performed in clinical routine but the possible influence of the mental state of the patient is never taken into account. We wanted to evaluate the effect of a mild psychological stress on solid phase gastric emptying in healthy young male volunteers. The standard meal consisted of a pancake (500 kJ) without additional liquid. Simultaneous dynamic acquisitions of gastric activity in anterior and posterior projection were taken during 90 min starting from the onset of the meal. Gastric emptying was evaluated three times in basal conditions and once under mental stress. Stress was induced by means of a dichotomous listening test, lasting for 30 min, starting at the end of the meal. The results of rest and stress studies were compared. Mild mental stress has a significant influence on gastric emptying. The lag phase increased from 11 +/- 3 min to 36 +/- 10 min (mean +/- S.D.) (p less than 0.005) and the gastric emptying rate from 79 +/- 13%/hour to 100 +/- 31%/hour (mean +/- S.D.) (not significant). During a stress period gastric emptying as a whole is delayed but this is mainly due to the prolongation of the lag phase. Our data also suggest that during the stress period gastric emptying is interrupted and reactivated once the stress period has ended.
放射性核素胃排空研究在临床常规中进行，但从未考虑患者精神状态的可能影响。我们想评估轻度心理应激对健康年轻男性志愿者固相胃排空的影响。标准餐由一个薄煎饼（500千焦）组成，不额外添加液体。从用餐开始起，在90分钟内同时在前位和后位投影下动态采集胃活动情况。在基础状态下评估胃排空三次，在心理应激状态下评估一次。应激通过二分听力测试诱导，从用餐结束开始，持续30分钟。比较休息和应激研究的结果。轻度心理应激对胃排空有显著影响。延迟期从11±3分钟增加到36±10分钟（平均值±标准差）（p<0.005），胃排空率从79±13%/小时增加到100±31%/小时（平均值±标准差）（无显著性差异）。在应激期间，胃排空总体上延迟，但这主要是由于延迟期延长。我们的数据还表明，在应激期间胃排空被中断，应激期结束后重新开始。
