Pickert Amanda J, Carpentieri David, Price Harper, Hansen Ronald C
Department of Dermatology, Mayo Clinic, Scottsdale, Arizona.
Pediatr Dermatol. 2014 Sep-Oct;31(5):591-4. doi: 10.1111/pde.12116. Epub 2013 Apr 29.
We report the case of a 2.5-year-old girl with linear morphea initially diagnosed as an acquired port-wine stain (PWS). She underwent three treatments to the right face using the pulsed dye laser (PDL) before sclerotic changes were observed and the correct diagnosis was confirmed with histopathology. Treatment using the PDL reduced the skin erythema but did not prevent subsequent sclerosis. The sclerosis became most prominent superior to the patient's right ear in an area not treated using the laser. A review of the English-language medical literature identified no cases of morphea triggered using a PDL, but there were several reports of early morphea misdiagnosed as an acquired PWS. Briefly, we review those cases, as well as morphea subtypes, and comment on how the pathophysiology of morphea may lend itself to an early underrecognized inflammatory presentation, delaying diagnosis.
我们报告了一例2.5岁患有线状硬皮病的女孩，最初被诊断为获得性葡萄酒色斑（PWS）。在观察到硬化改变并通过组织病理学确诊正确诊断之前，她使用脉冲染料激光（PDL）对右侧面部进行了三次治疗。使用PDL治疗减轻了皮肤红斑，但并未阻止随后的硬化。硬化在未接受激光治疗的患者右耳上方区域最为明显。对英文医学文献的回顾未发现使用PDL引发硬皮病的病例，但有几例早期硬皮病被误诊为获得性PWS的报告。简要地说，我们回顾了这些病例以及硬皮病的亚型，并评论了硬皮病的病理生理学如何可能导致早期未被充分认识的炎症表现，从而延迟诊断。
