Cicero Arrigo F, Tartagni Elisa, Ertek Sibel
Sant'Orsola-Malpighi University Hospital, Padiglione 2, Via Albertoni 15, 40138 Bologna-Italy.
Curr Vasc Pharmacol. 2014;12(4):565-71. doi: 10.2174/15701611113119990120.
Metabolic syndrome (MetS) is a world-wide epidemic disease associated with increased morbidity and mortality. Treatment strategies include pharmacologic and non-pharmacologic methods, with varying degrees of success rate all over the world. Pharmaceutical interest in this field is growing, together with patients' requests for supplementary (or "alternative") treatments. The knowledge of nutraceuticals beneficial effects in subjects with the MetS could help us to better define the appropriate treatment for these subjects, in particular those with contraindications for commonly used drugs, or to achieve guidelines suggested targets. On the other side, it could be not convenient to use a nutraceutical to treat each metabolic syndrome component (i.e. from 3 to 5) in each affected subjects. Thus, this review tries to focus on widely marketed nutraceuticals with clinically demonstrated effects on more than one component of the MetS, namely omega-3 fatty acids, berberine, psyllium and other soluble fibers, cinnamon, chromium picolinate, banaba, and bitter gourd.
代谢综合征（MetS）是一种全球性的流行病，与发病率和死亡率的增加相关。治疗策略包括药物治疗和非药物治疗方法，在世界各地的成功率各不相同。该领域的制药关注度不断提高，患者对补充（或“替代”）治疗的需求也在增加。了解营养保健品对代谢综合征患者的有益作用，有助于我们更好地确定这些患者的适当治疗方法，特别是那些对常用药物有禁忌症的患者，或实现指南建议的目标。另一方面，在每个受影响的个体中使用营养保健品来治疗代谢综合征的每个组成部分（即3至5个）可能并不方便。因此，本综述试图聚焦于在临床上已证明对代谢综合征多个组成部分有影响的广泛销售的营养保健品，即ω-3脂肪酸、黄连素、车前草和其他可溶性纤维、肉桂、吡啶甲酸铬、巴拿巴和苦瓜。
