Patti Angelo Maria, Al-Rasadi Khalid, Giglio Rosaria Vincenza, Nikolic Dragana, Mannina Carlo, Castellino Giuseppa, Chianetta Roberta, Banach Maciej, Cicero Arrigo F G, Lippi Giuseppe, Montalto Giuseppe, Rizzo Manfredi, Toth Peter P
Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
EuroMediterranean Institute of Science and Technology, Italy.
Arch Med Sci. 2018 Mar;14(2):422-441. doi: 10.5114/aoms.2017.68717. Epub 2017 Jul 19.
Metabolic syndrome (MetS) is characterized as a group of cardiometabolic risk factors that raise the risk for heart disease and other health problems, such as diabetes mellitus and stroke. Treatment strategies include pharmacologic interventions and supplementary (or "alternative") treatments. Nutraceuticals are derived from food sources (isolated nutrients, dietary supplements and herbal products) that are purported to provide health benefits, in addition to providing basic nutritional value. Nutraceuticals are claimed to prevent chronic diseases, improve health, delay the aging process, increase life expectancy, and support the structure and function of the body. The study of the beneficial effects of nutraceuticals in patients with MetS, including product standardization, duration of supplementation and definition of optimal dosing, could help better define appropriate treatment. This review focuses on widely marketed nutraceuticals (namely polyphenols, omega-3 fatty acids, macroelements and vitamins) with clinically demonstrated effects on more than one component of MetS.
代谢综合征(MetS)的特征是一组心脏代谢危险因素,这些因素会增加患心脏病和其他健康问题的风险,如糖尿病和中风。治疗策略包括药物干预和补充(或“替代”)疗法。营养保健品源自食物来源(分离出的营养素、膳食补充剂和草药产品),除了提供基本营养价值外,据称还具有健康益处。营养保健品据称可以预防慢性病、改善健康、延缓衰老过程、延长预期寿命并支持身体的结构和功能。研究营养保健品对代谢综合征患者的有益作用,包括产品标准化、补充持续时间和最佳剂量的定义,有助于更好地确定合适的治疗方法。本综述重点关注已广泛上市且对代谢综合征多个组成部分具有临床证实效果的营养保健品(即多酚、omega-3脂肪酸、宏量元素和维生素)。