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2 型糖尿病患者的营养:现有知识和待解决的挑战。

Nutrition in Patients with Type 2 Diabetes: Present Knowledge and Remaining Challenges.

机构信息

IRCCS-Azienda Ospedaliera di Bologna Sant'Orsola-Malpighi, I-40138 Bologna, Italy.

Department of Medical and Surgical Sciences, Alma Mater University of Bologna, I-40138 Bologna, Italy.

出版信息

Nutrients. 2021 Aug 10;13(8):2748. doi: 10.3390/nu13082748.

Abstract

Unhealthy behaviours, including diet and physical activity, coupled with genetic predisposition, drive type 2 diabetes (T2D) occurrence and severity; the present review aims to summarise the most recent nutritional approaches in T2D, outlining unmet needs. Guidelines consistently suggest reducing energy intake to counteract the obesity epidemic, frequently resulting in sarcopenic obesity, a condition associated with poorer metabolic control and cardiovascular disease. Various dietary approaches have been proposed with largely similar results, with a preference for the Mediterranean diet and the best practice being the diet that patients feel confident of maintaining in the long term based on individual preferences. Patient adherence is indeed the pivotal factor for weight loss and long-term maintenance, requiring intensive lifestyle intervention. The consumption of nutritional supplements continues to increase even if international societies do not support their systematic use. Inositols and vitamin D supplementation, as well as micronutrients (zinc, chromium, magnesium) and pre/probiotics, result in modest improvement in insulin sensitivity, but their use is not systematically suggested. To reach the desired goals, patients should be actively involved in the collaborative development of a personalised meal plan associated with habitual physical activity, aiming at normal body weight and metabolic control.

摘要

不健康的行为习惯,包括饮食和身体活动,加上遗传易感性,导致 2 型糖尿病(T2D)的发生和严重程度;本综述旨在总结 T2D 最新的营养方法,概述未满足的需求。指南一致建议减少能量摄入以对抗肥胖流行,这经常导致肌肉减少性肥胖,这种情况与较差的代谢控制和心血管疾病有关。已经提出了各种饮食方法,其结果大致相似,地中海饮食更受欢迎,最佳实践是根据个人喜好,让患者有信心在长期内维持的饮食。患者的坚持确实是减肥和长期维持的关键因素,需要强化生活方式干预。即使国际社会不支持系统使用营养补充剂,其消费仍在继续增加。肌醇和维生素 D 补充剂以及微量营养素(锌、铬、镁)和益生菌/益生元可适度改善胰岛素敏感性,但不建议系统使用。为了达到预期目标,患者应积极参与制定与习惯性身体活动相关的个性化膳食计划,以达到正常体重和代谢控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d217/8401663/15fe245211b0/nutrients-13-02748-g001.jpg

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