KTH Royal Institute of Technology, School of Chemical Science and Engineering, Fibre and Polymer Technology, Teknikringen 56-58, SE-100 44 Stockholm, Sweden.
Chem Soc Rev. 2013 Jul 7;42(13):5858-79. doi: 10.1039/c3cs60101c.
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been suggested for dendritic polymers, including theranostics, biosensors, optics, adhesives and coatings. The transition from potential to real applications is strongly dictated by their commercial accessibility, scaffolding ability as well as biocompatibility. A dendritic family that fulfills these requirements is based on the 2,2-bismethylolpropionic acid (bis-MPA) monomer. This critical review is the first of its kind to cover most of the research activities generated on aliphatic polyester dendritic architectures based on bis-MPA. It is apparent that these scaffolds will continue to be in the forefront of cutting-edge research as their structural variations are endless including dendrons, dendrimers, hyperbranched polymers, dendritic-linear hybrids and their hybridization with inorganic surfaces.
树枝状聚合物是高度支化的球状结构，具有多种官能团的代表。这些纳米级有机骨架继续吸引着全世界的研究人员，并且在应用驱动的研究中正在进行深入研究。已经为树枝状聚合物提出了大量潜在的应用领域，包括治疗学、生物传感器、光学、粘合剂和涂料。从潜在应用到实际应用的转变强烈取决于它们的商业可及性、支架能力以及生物相容性。满足这些要求的树枝状聚合物家族基于 2,2-双羟甲基丙酸（bis-MPA）单体。这篇评论是同类中的第一篇，涵盖了基于 bis-MPA 的脂肪族聚酯树枝状结构产生的大部分研究活动。显然，由于其结构变化无穷无尽，包括树枝状分子、树枝状聚合物、超支化聚合物、树枝状-线性杂化及其与无机表面的杂化，这些支架将继续处于前沿研究的最前沿。
