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RUbioSeq：一套并行管道，用于自动化外显子变异和亚硫酸氢盐测序分析。

RUbioSeq: a suite of parallelized pipelines to automate exome variation and bisulfite-seq analyses.

机构信息

Structural Computational Biology Group, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, 28029 Madrid, Spain.

出版信息

Bioinformatics. 2013 Jul 1;29(13):1687-9. doi: 10.1093/bioinformatics/btt203. Epub 2013 Apr 28.

DOI:10.1093/bioinformatics/btt203
PMID:23630175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3694642/
Abstract

MOTIVATION

RUbioSeq has been developed to facilitate the primary and secondary analysis of re-sequencing projects by providing an integrated software suite of parallelized pipelines to detect exome variants (single-nucleotide variants and copy number variations) and to perform bisulfite-seq analyses automatically. RUbioSeq's variant analysis results have been already validated and published.

AVAILABILITY

http://rubioseq.sourceforge.net/.

摘要

动机

RUbioSeq 的开发旨在通过提供一个集成的软件套件来简化重测序项目的初级和次级分析，该套件包含并行管道，用于检测外显子变体（单核苷酸变体和拷贝数变异）并自动执行亚硫酸氢盐测序分析。RUbioSeq 的变异分析结果已经经过验证并发表。

可用性

http://rubioseq.sourceforge.net/。

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