Intensive Care Unit, Royal Adelaide Hospital; Clinical Senior Lecturer, Discipline of Acute Care Medicine, University of Adelaide, Adelaide, Australia.
Int J Med Sci. 2013 Apr 17;10(6):747-50. doi: 10.7150/ijms.5868. Print 2013.
Commercial 0.9% saline solution for infusion has a pH around 5.5. There are many reasons for this acidity, some of them still obscure. It is also true that infusion of normal saline can lead to metabolic acidaemia, yet the link between the acidity of saline solution and the acidaemia it can engender is not straightforward. This commentary draws together the known and putative sources of acidity in saline solutions: it turns out that the acidity of saline solution is essentially unrelated to the acidaemia complicating saline infusion.
商业用 0.9%生理盐水的 pH 值约为 5.5。造成这种酸度的原因有很多,其中一些原因仍不清楚。而且,输注生理盐水确实会导致代谢性酸中毒,但生理盐水的酸度与其可能引起的酸中毒之间的关系并不简单。本评论总结了生理盐水溶液中已知和推测的酸度来源:事实证明,生理盐水溶液的酸度与输注生理盐水引起的酸中毒基本无关。