Wang Fuke, Nimmo Susan L, Cao Binrui, Mao Chuanbin
Department of Chemistry & Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019, USA.
Chem Sci. 2012 Aug 1;3(8):2639-2645. doi: 10.1039/C2SC00583B.
Biomimetic silica formation is strongly dependent on the presence of cationic amine groups which hydrolyze organosilicate precursors and bind to silicate oligomers. Since most biological species possess anionic surfaces, the dependence on amine groups limits utilization of biotemplates for fabricating materials with specific morphologies and pore structures. Here, we report a general aminopropyltriethoxysilane (APTES) directed method for preparing hollow silica with well-defined morphologies using varying biotemplates (proteins, viruses, flagella, bacteria and fungi). Control experiments, pH evolution measurements and Si NMR spectroscopic studies have revealed a mechanism of the assembly of APTES on bio-surfaces with subsequent nucleation and growth of silica. The APTES assembly and nuclei formation on bio-surfaces ensured precise transcription of the morphologies of biotemplates to the resulting silica. This method could be extended to the preparation of other oxides.
仿生二氧化硅的形成强烈依赖于阳离子胺基的存在，这些胺基能水解有机硅酸盐前体并与硅酸盐低聚物结合。由于大多数生物物种具有阴离子表面，对胺基的依赖限制了生物模板在制造具有特定形态和孔结构材料方面的应用。在此，我们报道了一种通用的氨丙基三乙氧基硅烷（APTES）导向方法，该方法使用不同的生物模板（蛋白质、病毒、鞭毛、细菌和真菌）制备具有明确形态的中空二氧化硅。对照实验、pH值变化测量和硅核磁共振光谱研究揭示了APTES在生物表面组装以及随后二氧化硅成核和生长的机制。APTES在生物表面的组装和成核确保了生物模板的形态精确转录到所得二氧化硅上。该方法可扩展到其他氧化物的制备。
