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[麻疹、腮腺炎、风疹联合疫苗接种后的反应]

[Reactions after MMR vaccination].

作者信息

Kaaber K, Samuelsson I S, Larsen S O

机构信息

Statens Seruminstitut, København, Epidemiologisk afdeling og biostatistisk afdeling.

出版信息

Ugeskr Laeger. 1990 Jun 4;152(23):1672-6.

PMID:2363211
Abstract

Four months after introducing routine vaccination against measles, mumps and German measles (MMR-vaccination) in Denmark, a questionnaire study of reactions in vaccinated children was carried out. There were significantly fewer reactions in children who had previously developed immunity to measles, either by having had the disease or by vaccination. The reaction frequency after MMR-vaccination of children immune to measles was no greater than that after other vaccinations. Moreover, for all vaccinations, the frequency of reaction was found to decrease significantly with increasing age. The study suggests that a large proportion of the so-called reactions were not caused by vaccination, but were due to common viral infections occurring at random and concurrently with it. The reactions that arose in connection with MMR-vaccination are considered to be of minor importance when compared with often prolonged and more severe course of these diseases.

摘要

在丹麦引入麻疹、腮腺炎和风疹(MMR)常规疫苗接种四个月后,对接种疫苗儿童的反应进行了问卷调查研究。以前通过患过麻疹或接种疫苗而获得麻疹免疫力的儿童,其接种后的反应明显较少。对麻疹有免疫力的儿童接种MMR疫苗后的反应频率并不高于其他疫苗接种后的反应频率。此外,对于所有疫苗接种,发现反应频率会随着年龄的增长而显著降低。该研究表明,很大一部分所谓的反应并非由疫苗接种引起,而是由于与疫苗接种同时随机发生的常见病毒感染所致。与这些疾病通常较长且更严重的病程相比,与MMR疫苗接种相关的反应被认为不太重要。

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