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应用相敏谱域光学相干断层成像术对正常人视神经乳头搏动性运动的无创性成像研究。

Noninvasive imaging of pulsatile movements of the optic nerve head in normal human subjects using phase-sensitive spectral domain optical coherence tomography.

机构信息

Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.

出版信息

Opt Lett. 2013 May 1;38(9):1512-4. doi: 10.1364/OL.38.001512.

DOI:10.1364/OL.38.001512
PMID:23632535
Abstract

We report use of high-speed spectral domain optical coherence tomography to noninvasively image pulsatile axial movement of the optic nerve head (ONH) in normal human subjects. Time-lapse B-scan mode is used to image the ONH at 500 frames per second. Capture of phase differences between adjacent B-scans permits extraction of axial ONH movement. We find the ONH experiences continuous oscillatory axial motion that is strongly correlated with simultaneously measured pulsatile blood flow in the central retinal artery.

摘要

我们报告了使用高速谱域光学相干断层扫描技术无创地成像正常人眼视神经头(ONH)的脉动轴向运动。使用时变 B 扫描模式每秒对 ONH 成像 500 帧。相邻 B 扫描之间的相位差的捕获允许提取轴向 ONH 运动。我们发现 ONH 经历与同时测量的中央视网膜动脉的脉动血流强烈相关的连续振荡轴向运动。

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