多普勒光学相干断层扫描技术验证了人体视网膜中搏动诱导的各向异性血管腔动态变化。
Doppler OCT verifies pulsation-induced anisotropic vessel lumen dynamics in the human retina.
作者信息
Adejumo Tobiloba, Son Taeyoon, Ma Guangying, Rahimi Mojtaba, Dadzie Albert, Ding Jie, Yao Xincheng
出版信息
Opt Lett. 2025 Jun 15;50(12):3903-3906. doi: 10.1364/OL.555324.
Abstract
This study verifies anisotropic vessel pulsatility in human retinas. Doppler optical coherence tomography (OCT) was utilized for dynamic monitoring of peripapillary vessel lumen dynamics. Quantitative analysis consistently revealed larger axial compared to lateral lumen changes, with an axial-to-lateral pulsation change ratio of 1.26 ± 0.08. These findings highlight the anisotropic biomechanical properties of retinal tissues, which contribute to direction-dependent vascular dynamics. Quantitative assessment of anisotropic vascular biomechanics offers promising insights for improving the detection of vascular alterations associated with ocular conditions.
摘要
本研究验证了人视网膜中血管搏动的各向异性。利用多普勒光学相干断层扫描（OCT）对视乳头周围血管腔动态进行动态监测。定量分析一致显示，轴向管腔变化比横向管腔变化更大，轴向与横向搏动变化比为1.26±0.08。这些发现突出了视网膜组织的各向异性生物力学特性，这有助于方向依赖性血管动力学。对各向异性血管生物力学的定量评估为改善与眼部疾病相关的血管改变的检测提供了有前景的见解。
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