Department of Pharmacology, Taipei Medical University, Taipei 110, Taiwan.
Evid Based Complement Alternat Med. 2013;2013:846740. doi: 10.1155/2013/846740. Epub 2013 Mar 24.
Andrographis paniculata (Burm. F) Nees, generally known as "king of bitters," is an herbaceous plant in the family Acanthaceae. In China, India, Thailand, and Malaysia, this plant has been widely used for treating sore throat, flu, and upper respiratory tract infections. Andrographolide, a major bioactive chemical constituent of the plant, has shown anticancer potential in various investigations. Andrographolide and its derivatives have anti-inflammatory effects in experimental models asthma, stroke, and arthritis. In recent years, pharmaceutical chemists have synthesized numerous andrographolide derivatives, which exhibit essential pharmacological activities such as those that are anti-inflammatory, antibacterial, antitumor, antidiabetic, anti-HIV, antifeedant, and antiviral. However, what is noteworthy about this paper is summarizing the effects of andrographolide against cardiovascular disease, platelet activation, infertility, and NF- κ B activation. Therefore, this paper is intended to provide evidence reported in relevant literature on qualitative research to assist scientists in isolating and characterizing bioactive compounds.
穿心莲（Burm. F） Nees，通常被称为“苦中之王”，是爵床科的一种草本植物。在中国、印度、泰国和马来西亚，这种植物被广泛用于治疗喉咙痛、流感和上呼吸道感染。穿心莲内酯是植物中的一种主要生物活性化学成分，在各种研究中显示出抗癌潜力。穿心莲内酯及其衍生物在哮喘、中风和关节炎等实验模型中具有抗炎作用。近年来，药物化学家合成了许多穿心莲内酯衍生物，这些衍生物具有重要的药理活性，如抗炎、抗菌、抗肿瘤、抗糖尿病、抗 HIV、抗虫和抗病毒。然而，本文的重要之处在于总结了穿心莲内酯对心血管疾病、血小板活化、不孕和 NF-κB 激活的作用。因此，本文旨在提供相关文献中关于定性研究的报告结果，以协助科学家分离和鉴定生物活性化合物。
