Okeke Tc, Anyaehie Ub, Ezenyeaku Cc
Department of Obstetrics and Gynecology, University of Nigeria Teaching Hospital, Enugu, Nigeria ; Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Awka, Nigeria.
Ann Med Health Sci Res. 2013 Jan;3(1):90-5. doi: 10.4103/2141-9248.109458.
Premature menopause affects 1% of women under the age of 40 years. The women are at risk of premature death, neurological diseases, psychosexual dysfunction, mood disorders, osteoporosis, ischemic heart disease and infertility. There is need to use simplified protocols and improved techniques in oocyte donation to achieve pregnancy and mother a baby in those women at risk. Review of the pertinent literature on premature menopause, selected references, internet services using the PubMed and Medline databases were included in this review. In the past, pregnancy in women with premature menopause was rare but with recent advancement in oocyte donation, women with premature menopause now have hoped to mother a child. Hormone replacement therapy is beneficial to adverse consequences of premature menopause. Women with premature menopause are at risk of premature death, neurological diseases, psychosexual dysfunction, mood disorders, osteoporosis, ischemic heart disease and infertility. Public enlightenment and education is important tool to save those at risk.
过早绝经影响1%的40岁以下女性。这些女性面临过早死亡、神经系统疾病、性心理功能障碍、情绪障碍、骨质疏松症、缺血性心脏病和不孕不育的风险。有必要采用简化方案和改进技术进行卵母细胞捐赠，以使这些有风险的女性实现妊娠并生育宝宝。本综述纳入了对有关过早绝经的相关文献、选定参考文献以及使用PubMed和Medline数据库的互联网服务的回顾。过去，过早绝经女性怀孕的情况很罕见，但随着最近卵母细胞捐赠技术的进步，过早绝经女性现在有望生育孩子。激素替代疗法对过早绝经的不良后果有益。过早绝经女性面临过早死亡、神经系统疾病、性心理功能障碍、情绪障碍、骨质疏松症、缺血性心脏病和不孕不育的风险。公众宣传和教育是拯救这些有风险人群的重要工具。
