Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Women's Hospital of the University of Pittsburgh Medical Center, and Magee-Women's Research Institute, Pittsburgh, Pittsburgh.
Obstet Gynecol. 2013 Apr;121(4):734-740. doi: 10.1097/AOG.0b013e31828642b1.
To estimate whether text messages sent to ambulatory pregnant women could improve influenza vaccine uptake.
Obstetric patients at less than 28 weeks of gestation were enrolled in a randomized controlled trial from an academic center's outpatient clinic during two consecutive influenza seasons (2010-2011 and 2011-2012). Potential participants were excluded if they had already received that season's influenza vaccine. Participants were randomized to receive 12 weekly text messages encouraging general pregnancy health (General) or general pregnancy health plus influenza vaccination (Flu). Study participants completed preintervention and postintervention surveys about preventive health beliefs. Influenza vaccine receipt was assessed using prenatal record review. The study was powered to detect a 55% increase in the vaccination rate in the intervention group.
Two hundred sixteen women were enrolled, 204 of whom were available for intention-to-treat analysis (n=100 General, n=104 Flu). Participants were primarily African American (66%) with low educational attainment (90% equivalent to or less than high school education) and predominantly with either public or no insurance (88%). The overall influenza vaccination rate among participants was 32% with no difference between participants in the General (31% [n=31]) compared with Flu (33% [n=34]) groups (difference 1.7%, 95% confidence interval -11.1 to 14.5%).
Text messaging prompts were not effective at increasing influenza vaccination rates among a low-income, urban, ambulatory obstetric population. Ongoing efforts are needed to improve vaccine uptake among pregnant women unsure about or unwilling to receive influenza vaccination.
ClinicalTrials.gov, www.clinicaltrials.gov, NCT01248520.
: I.
评估向门诊孕妇发送短信是否可以提高流感疫苗接种率。
在两个连续的流感季节（2010-2011 年和 2011-2012 年），从学术中心的门诊招募妊娠不到 28 周的产科患者参加一项随机对照试验。如果参与者已经接种了该季节的流感疫苗，则将其排除在外。参与者被随机分配接受 12 周的每周短信，内容是鼓励一般妊娠健康（普通）或一般妊娠健康加流感疫苗接种（流感）。研究参与者在干预前后完成关于预防保健信念的调查。使用产前记录审查评估流感疫苗接种情况。该研究有足够的能力检测到干预组疫苗接种率增加 55%。
共纳入 216 名女性，其中 204 名可进行意向治疗分析（n=100 普通，n=104 流感）。参与者主要为非裔美国人（66%），受教育程度低（90%相当于或低于高中教育），主要拥有公共或无保险（88%）。参与者的总体流感疫苗接种率为 32%，普通组（31%[n=31]）与流感组（33%[n=34]）之间无差异（差异 1.7%，95%置信区间-11.1 至 14.5%）。
在低收入、城市、门诊产科人群中，短信提示并不能有效提高流感疫苗接种率。需要继续努力提高对流感疫苗接种不确定或不愿意接种的孕妇的疫苗接种率。
ClinicalTrials.gov，www.clinicaltrials.gov，NCT01248520。
I。
