Nakamura Munetaka, Nishikawa Jun, Goto Atsushi, Nishimura Junichi, Hashimoto Shinichi, Okamoto Takeshi, Sakaida Isao
Department of Gastroenterology & Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, Yamaguchi, 755-8505, Japan.
J Gastrointest Cancer. 2013 Sep;44(3):325-8. doi: 10.1007/s12029-013-9500-z.
Transnasal endoscopy with ultraslim endoscope has rapidly spread in Japan. Ultraslim endoscopy provides less resolution than that of conventional endoscopy and may lead to missed screening of early gastric carcinoma. We evaluated the efficacy of ultraslim endoscopy with flexible spectral imaging color enhancement (FICE) for the diagnosis of early gastric carcinoma.
This study included 20 consecutive patients in whom 22 gastric neoplasms were resected by endoscopic submucosal dissection (ESD) between April 2011 and January 2012 in Yamaguchi University Hospital. Prior to ESD, marking dots were made during observation with ultraslim endoscopy with FICE. We evaluated en bloc resection rate and tumor visibility with the FICE system.
All tumors were resected with sufficient lateral margin. Only one case had tumor cells in the vertical margin. En bloc resection rate was 95.5 % (21/22 lesions). Ultraslim endoscopy with FICE more clearly visualized tumor margin than did conventional endoscopy. Especially, the effect was remarkable in discolored lesions (100.0 %, 3/3 lesions).
Ultraslim endoscopy with FICE improved visibility of gastric neoplasms.
超细内镜经鼻内镜检查在日本已迅速普及。超细内镜的分辨率低于传统内镜，可能导致早期胃癌筛查漏诊。我们评估了带有灵活光谱成像色彩增强（FICE）技术的超细内镜对早期胃癌的诊断效果。
本研究纳入了2011年4月至2012年1月间在山口大学医院连续接受内镜下黏膜剥离术（ESD）切除22个胃肿瘤的20例患者。在ESD术前，使用带有FICE技术的超细内镜观察时标记出标记点。我们评估了整块切除率以及FICE系统下肿瘤的可视性。
所有肿瘤均获得足够的侧切缘切除。仅1例垂直切缘有肿瘤细胞。整块切除率为95.5%（21/22个病变）。与传统内镜相比，带有FICE技术的超细内镜能更清晰地显示肿瘤边缘。特别是在变色病变中效果显著（100.0%，3/3个病变）。
带有FICE技术的超细内镜提高了胃肿瘤的可视性。
