National Evidence-based Healthcare Collaborating Agency, Seoul, South Korea.
Obes Surg. 2013 Dec;23(12):2058-67. doi: 10.1007/s11695-013-0971-6.
In South Korea, the number of severely obese patients has increased. An economic study comparing bariatric surgery with nonsurgical interventions has not been published for Asia.
This study was conducted to evaluate the cost effectiveness of bariatric surgery as compared to nonsurgical interventions for severe obese Korean people.
We used the Markov model to compare the lifetime expected costs and quality-adjusted life years (QALYs) between bariatric surgery and nonsurgical interventions from Korean Healthcare system perspectives. Our target cohort consisted of severe obese people defined as having a body mass index of 30-<40 kg/m(2) in South Korea. The starting age of the cohort was 30 years old, and the cycle length was 1 year. Nonsurgical interventions included a physician visit, exercise, diet, and pharmacotherapy. A discount of 5 % was applied in cost and QALY. The incremental cost-effectiveness ratio (ICER) of bariatric surgery compared to nonsurgery interventions was calculated.
The cost-utility analysis study indicated that bariatric surgery had US$1,522 incremental costs and 0.86 incremental QALYs as compared to nonsurgical interventions. Through the base case analysis, ICER was US$1,771/QALY. The sensitivity analyses were performed using a variety of assumptions, and the robustness of the study results was also demonstrated.
The study indicated that bariatric surgery was a cost-effective alternative to nonsurgical interventions over a lifetime, providing substantial lifetime benefits for severely obese Korean people.
在韩国,重度肥胖患者的数量有所增加。亚洲尚未发表过比较减肥手术与非手术干预措施的经济学研究。
本研究旨在评估减肥手术与非手术干预措施相比,用于韩国重度肥胖人群的成本效果。
我们使用马尔可夫模型,从韩国医疗保健系统的角度比较了减肥手术与非手术干预措施的终身预期成本和质量调整生命年(QALY)。我们的目标队列由韩国定义的重度肥胖人群组成,体重指数为 30-<40kg/m²。队列的起始年龄为 30 岁,周期长度为 1 年。非手术干预包括医生就诊、运动、饮食和药物治疗。成本和 QALY 均采用 5%的贴现率。计算了减肥手术与非手术干预相比的增量成本效果比(ICER)。
成本效用分析研究表明,与非手术干预相比,减肥手术具有 1522 美元的增量成本和 0.86 的增量 QALY。通过基础案例分析,ICER 为 1771 美元/QALY。进行了各种假设的敏感性分析,也证明了研究结果的稳健性。
研究表明,对于韩国重度肥胖人群,减肥手术是一种比非手术干预更具成本效果的选择,可提供显著的终身获益。