Skin and Laser Center, Boom, Belgium.
Dermatol Surg. 2013 Aug;39(8):1209-16. doi: 10.1111/dsu.12238. Epub 2013 May 2.
Comprehensive assessment of safety, tolerance, and patient satisfaction has not been established from noninvasive body contouring techniques, such as low-level laser therapy, ultrasound, radiofrequency, and infrared light, for reduction of subcutaneous fat.
This multicenter study investigated the clinical outcomes of noninvasive cryolipolysis in European subjects.
A retrospective study was performed at clinical sites in Belgium and France. Safety was assessed according to reports of side effects. Tolerance was evaluated according to pain scores and patient perception of treatment duration. Clinical outcomes were assessed according to patient surveys, caliper measurements, and assessment of photographs.
The investigators treated 518 patients. No significant side effects or adverse events were reported. The procedure was well-tolerated, with 89% of respondents reporting a positive perception of treatment duration and 96% reporting minimal to tolerable discomfort. Survey results demonstrated 73% patient satisfaction and that 82% of patients would recommend the cryolipolysis procedure to a friend. Caliper measurements demonstrated 23% reduction in fat layer thickness at 3 months. Abdomen, back, and flank treatment sites were most effective, with 86% of subjects showing improvement per investigator assessment.
With proper patient selection, cryolipolysis is a safe, well-tolerated, and effective treatment method for reduction of subcutaneous fat.
对于减少皮下脂肪的非侵入性身体塑形技术，如低水平激光疗法、超声波、射频和红外线，尚未从安全性、耐受性和患者满意度方面进行全面评估。
本多中心研究调查了欧洲受试者中无创性冷冻溶脂的临床效果。
在比利时和法国的临床中心进行了回顾性研究。根据不良反应报告评估安全性。根据疼痛评分和患者对治疗持续时间的感知评估耐受性。根据患者调查、卡尺测量和照片评估来评估临床结果。
研究人员治疗了 518 名患者。未报告明显的副作用或不良事件。该过程耐受性良好，89%的受访者对治疗持续时间有积极的感知，96%的受访者报告轻微至可耐受的不适。调查结果显示 73%的患者满意度，82%的患者会向朋友推荐冷冻溶脂程序。卡尺测量显示，3 个月时脂肪层厚度减少 23%。腹部、背部和侧腹治疗部位效果最佳，86%的受试者经研究者评估显示有改善。
在适当的患者选择下，冷冻溶脂是一种安全、耐受性良好且有效的减少皮下脂肪的治疗方法。
