Hildesheimer M, Bloch F, Muchnik C, Rubinstein M
School of Communication Disorders, Speech, Language and Hearing, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Arch Otolaryngol Head Neck Surg. 1990 Jul;116(7):820-3. doi: 10.1001/archotol.1990.01870070068012.
Two groups of 33 subjects each, one experimental and one control, matched one-to-one for age and occupation, were chosen from a large number of subjects who were covered by special insurance for annual medical control at our hospital. The periodical checkups included cardiovascular, nervous, and renal systems, as well as vision and hearing. In addition routine blood tests, including whole blood viscosity, were also performed. The experimental group consisted of subjects in whom a bilateral, slight, and unexplained sensorineural loss of hearing was detected in the routine audiological testing, without any known reason. In the control group, the routine hearing tests demonstrated normal hearing. The differences between the two groups were statistically significant in pure-tone threshold level and in speech discrimination score, when the test was performed at a -5dB signal-to-noise ratio. The results of the vestibular tests were normal in both groups. Hematocrit and whole blood viscosity were slightly but significantly higher in the experimental group if compared with the control group. The number of subjects with abnormal whole blood viscosity results was higher in the experimental group. The whole blood viscosity as the etiological factor responsible for the hearing deterioration is described.
从我院享受年度体检专项保险的大量受检者中，选取了两组受试者，每组各33人，一组为实验组，一组为对照组，两组在年龄和职业上一一匹配。定期检查包括心血管系统、神经系统、肾脏系统以及视力和听力。此外，还进行了包括全血粘度在内的常规血液检查。实验组由在常规听力测试中检测出双侧、轻度且原因不明的感音神经性听力损失的受试者组成，无任何已知病因。对照组的常规听力测试显示听力正常。当测试在信噪比为 -5dB 时进行，两组在纯音阈值水平和言语辨别得分方面的差异具有统计学意义。两组的前庭测试结果均正常。与对照组相比，实验组的血细胞比容和全血粘度略高但差异显著。实验组中全血粘度结果异常的受试者数量更多。文中描述了将全血粘度作为导致听力恶化的病因因素。
