Rhinology Unit & Smell Clinic, Department of Otorhinolaryngology, Hospital Clínic i Universitari, University of Barcelona, Barcelona, Catalonia, Spain.
Immunol Allergy Clin North Am. 2013 May;33(2):163-76. doi: 10.1016/j.iac.2012.11.002. Epub 2012 Dec 23.
The presence of aspirin-exacerbated respiratory disease (AERD) in a patient with chronic rhinosinusitis with nasal polyps and asthma is associated with severe eosinophilic upper and lower airway disease. This article deals with the inflammatory disease of the respiratory tract as it relates to the sinuses. Involvement of the sinuses in AERD is almost universal, depending on the stage of onset of the disease and evaluation by computed tomography. This article explores the clinical aspects, physiopathology, and treatment of rhinosinusitis as it relates to AERD.
阿司匹林加重性呼吸系统疾病(AERD)在伴有鼻息肉和哮喘的慢性鼻-鼻窦炎患者中的存在与严重的嗜酸性粒细胞性上下呼吸道疾病相关。本文涉及与鼻窦相关的呼吸道炎症性疾病。根据疾病的发病阶段和计算机断层扫描评估,鼻窦受累在 AERD 中几乎是普遍存在的。本文探讨了与 AERD 相关的鼻-鼻窦炎的临床方面、病理生理学和治疗。