伊朗西部克尔曼沙阿省转诊至医院患者的甲癣感染发病率

The Incidence of Onychomycosis Infection among Patients Referred to Hospitals in Kermanshah Province, Western Iran.

作者信息

Mikaeili Ali, Karimi Isaac

机构信息

Dept. of Medical Mycology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Iran J Public Health. 2013 Mar 1;42(3):320-5. Print 2013.

PMID:23641410

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3633803/

Abstract

BACKGROUND

Onychomycosis is a nail disorder associated with aesthetic problems, discomfort, physical injury and loss of dexterity. The purpose of the present study was to isolate and identify the causative fungi of onychomycosis in 2402 patients in Kermanshah Province, western Iran in 1994 to 2010.

METHODS

Mycologic assessment was carried out by standard methods including either microscopic or cultural procedures.

RESULTS

Direct microscopy of the nail clips was positive in 1086 (45.2%) and fingernail and toenail onychomycoses were recognized in 773 (71.1%) and 313 (28.8%), respectively. Yeasts were detected in 853 (78.5%), dermatophytes in 201 (18.5%) and non-dermatophyte fungi in 32 (2.9%) patients. The results of fungal culture showed Candida albicans isolated in 384 (45.0%) and other Candida spp. isolated in 361 (54.0%) of the cases as the most common agents of onychomycosis while among dermatophytes, Trichophyton rubrum was found in 63 (37.0%) of the cases as the main dermatophytic agent followed by T. mentagrophytes 32 (15.9%) and Epidermophyton flocosum 30 (17.6%). Among the non-dermatophyte moulds, Aspergillus flavus was the most prevalent species 12 (37.5%) followed by A. niger 8 (25.0%) and A. fumigatus 4 (12.5%). Moreover, 139 (12.8%) samples with positive direct microscopy yielded no growth. The highest rate of onychomycosis was found in patients between 30-40 years of age.

CONCLUSION

In sum, the current results identified the aetiological agents and primary epidemiological aspects of onychomycosis in west Iran.

摘要

背景

甲癣是一种与美观问题、不适、身体损伤及灵活性丧失相关的指甲疾病。本研究的目的是分离并鉴定1994年至2010年期间伊朗西部克尔曼沙赫省2402例甲癣患者的致病真菌。

方法

采用包括显微镜检查或培养程序在内的标准方法进行真菌学评估。

结果

指甲夹的直接显微镜检查阳性率为1086例（45.2%），手指甲和脚趾甲甲癣的确诊率分别为773例（71.1%）和313例（28.8%）。在853例（78.5%）患者中检测到酵母菌，201例（18.5%）为皮肤癣菌，32例（2.9%）为非皮肤癣菌真菌。真菌培养结果显示，白色念珠菌在384例（45.0%）病例中分离得到，其他念珠菌属在361例（54.0%）病例中分离得到，是甲癣最常见的病原体；而在皮肤癣菌中，红色毛癣菌在63例（37.0%）病例中被发现是主要的皮肤癣菌病原体，其次是须癣毛癣菌32例（15.9%）和絮状表皮癣菌30例（17.6%）。在非皮肤癣菌霉菌中，黄曲霉是最常见的菌种，有12例（37.5%），其次是黑曲霉8例（25.0%）和烟曲霉4例（12.5%）。此外，139例（12.8%）直接显微镜检查阳性的样本未生长出真菌。甲癣发病率最高的是年龄在30至40岁之间的患者。