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欧洲制造:青蒿素耐药性会在法属圭亚那出现吗?

Made in Europe: will artemisinin resistance emerge in French Guiana?

机构信息

Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane CIC-EC CIE 802, Cayenne General Hospital, Cayenne, French Guiana.

出版信息

Malar J. 2013 May 4;12:152. doi: 10.1186/1475-2875-12-152.

Abstract

Resistance to artemisinin casts a shadow on the fight against malaria. The importance of illegal gold miners and of malaria in isolated regions of French Guiana constitutes a threat that endangers the fight against malaria in the Amazon. The hurdles of French laws and the remoteness of the territory from France make it impossible for the system to adapt to the problem of total inaccessibility of an important part of the malaria problem. Transmission is high in these areas and gold miners self-medicate with erratic regimens of artemisinin combinations, thus creating perfect conditions for the emergence of resistance. What needs to be done is being done, but within the limits of national law, with some results. However, facing the same difficult problem, Suriname shows more flexibility and is doing much better than French Guiana despite having lower resources. Local authorities in French Guiana cannot overrule the laws that block appropriate malaria care from reaching a third of malaria-exposed persons. Thus the health authorities in France should take immediate calibrated legislative and financial measures to avoid a predictable disaster.

摘要

抗疟药物青蒿素的耐药性给疟疾防治工作蒙上了阴影。非法金矿开采和法属圭亚那偏远地区疟疾的重要性构成了一种威胁,危及到亚马逊地区的疟疾防治工作。法国法律的障碍以及该领土与法国的距离遥远,使得该体系无法适应疟疾问题的重要部分完全无法到达的问题。这些地区的传播率很高,金矿工人自行服用青蒿素联合药物的不规则方案,从而为耐药性的出现创造了完美的条件。正在做需要做的事情,但在国家法律的范围内,取得了一些成果。然而,面对同样的困难问题,苏里南比法属圭亚那更灵活,表现更好,尽管资源较少。法属圭亚那地方当局无法推翻阻止三分之一疟疾暴露者获得适当疟疾治疗的法律。因此,法国卫生当局应立即采取有针对性的立法和财政措施,以避免可预见的灾难。

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