Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas & Universidad Miguel Hernández, Sant Joan d'Alacant 03550, Spain.
Cell Stem Cell. 2013 May 2;12(5):497-9. doi: 10.1016/j.stem.2013.04.017.
In this issue, Maroof et al. (2013) and Nicholas et al. (2013) describe strategies for deriving cortical interneurons from human pluripotent stem cells. Functional maturation of these neurons occurs over a protracted period, which resembles normal human development, and suggests these cells may be useful for modeling brain development and disease.
在本期中，Maroof 等人（2013 年）和 Nicholas 等人（2013 年）描述了从人类多能干细胞中获得皮质中间神经元的策略。这些神经元的功能成熟需要经过一个漫长的过程，类似于正常的人类发育，这表明这些细胞可能可用于模拟大脑发育和疾病。
