Departments of Ophthalmology, Gaziosmanpasa University Faculty of Medicine, Tokat, Turkey.
Cont Lens Anterior Eye. 2013 Oct;36(5):219-25. doi: 10.1016/j.clae.2013.04.001. Epub 2013 Apr 30.
To determine the efficacy of different Galilei Scheimpflug-Analyzer (GSA) parameters in discriminating between keratoconic and myopic eyes.
GSA measurements were obtained for 67 patients (67 eyes) with keratoconus and 151 patients (151 eyes) with myopia or myopic astigmatism. Several parameters, provided by the software or derived from the elevation maps, were evaluated and compared for the two groups.
Between the two groups, statistically significant differences were observed for all corneal parameters obtained by GSA (P<0.001) except for the anterior chamber depth (P=0.149). ROC analysis determined that posterior corneal elevation was the best predictive parameter (area under the curve: 0.99). The posterior corneal elevation, at a cut-off value of 18.5μm, had 98.5% sensitivity and 98.3% specificity in discriminating keratoconus from myopic eyes.
Elevation, pachymetric and keratometric parameters measured by the GSA, as well as the specific predictive GSA software parameters can effectively distinguish advanced keratoconus from myopic corneas. Also, keratoconus that is easily diagnosed by other means can be diagnosed easily by GSA software parameters.
确定不同的 Galilei Scheimpflug 分析仪（GSA）参数在区分圆锥角膜和近视眼中的功效。
对 67 例圆锥角膜患者（67 只眼）和 151 例近视或近视散光患者（151 只眼）进行 GSA 测量。评估并比较了两组的几种由软件提供或从高度图中得出的参数。
两组之间，所有由 GSA 获得的角膜参数均存在统计学显著差异（P<0.001），除前房深度（P=0.149）外。ROC 分析确定，后表面角膜高度是最佳预测参数（曲线下面积：0.99）。在后表面角膜高度的截断值为 18.5μm 时，区分圆锥角膜与近视眼的敏感性为 98.5%，特异性为 98.3%。
GSA 测量的高度、厚度和角膜曲率参数以及 GSA 软件的特定预测参数可有效区分进展期圆锥角膜与近视角膜。此外，通过其他手段容易诊断的圆锥角膜也可以通过 GSA 软件参数轻松诊断。
