Department of Cardiology and Neurology of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Complement Ther Med. 2013 Jun;21(3):155-7. doi: 10.1016/j.ctim.2013.02.001. Epub 2013 Mar 13.
We investigated apipuncture, or acupuncture point injection with diluted bee venom, as a promising new treatment for central post stroke pain (CPSP).
Bee venom, diluted to 0.005% in normal saline, was administered to the treatment group, and normal saline given to control group as twice-weekly injections for three weeks. The points were LI15, GB21, LI11, GB31, ST36 and GB39 of the affected side and the amount of injection was 0.05 ml at each point.
Eight patients in each group were included in the analysis. After three weeks there were significant decreases in visual analogue pain scores compared with baseline in both groups and the treatment group improved more significantly than the control group (p = 0.009).
Apipuncture significantly improved CPSP in this pilot trial. Further studies of its mechanisms and a larger and long-term follow-up trial will be needed to determine more definitely the efficacy of apipuncture and to elucidate duration of improvement.
我们研究蜂针疗法，即使用稀释的蜂毒液进行穴位注射，作为治疗中风后中枢性疼痛（CPSP）的一种有前途的新方法。
将蜂毒液稀释至 0.005%的生理盐水，注射到治疗组，对照组给予生理盐水，每周两次，连续三周。穴位为患侧 LI15、GB21、LI11、GB31、ST36 和 GB39，每个穴位注射 0.05 毫升。
每组各有 8 名患者纳入分析。与基线相比，两组患者在治疗 3 周后视觉模拟疼痛评分均显著下降，且治疗组的改善明显优于对照组（p = 0.009）。
在这项初步试验中，蜂针疗法显著改善了 CPSP。需要进一步研究其机制，并进行更大规模和长期随访试验，以更确定地确定蜂针疗法的疗效，并阐明改善的持续时间。
