Department of Cardiovascular and Neurologic Diseases, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Parkinsonism Relat Disord. 2012 Sep;18(8):948-52. doi: 10.1016/j.parkreldis.2012.04.030. Epub 2012 May 24.
This study aimed to explore the effectiveness of both acupuncture and bee venom acupuncture as adjuvant therapies for idiopathic Parkinson's disease. We recruited 43 adults with idiopathic Parkinson's disease who had been on a stable dose of antiparkinsonian medication for at least 1 month. They were randomly assigned to 1 of 3 groups: acupuncture, bee venom acupuncture, or control. All participants were assessed using the Unified Parkinson's Disease Rating Scale, the Parkinson's Disease Quality of Life Questionnaire, the Beck Depression Inventory, the Berg Balance Scale, and the time and number of steps required to walk 30 m. Treatment groups underwent stimulation of 10 acupuncture points using acupuncture or bee venom acupuncture twice a week for 8 weeks. The initial assessment was repeated at the completion of treatment. The control group did not receive any treatment. Participants in the bee venom acupuncture group showed significant improvement on the Unified Parkinson's Disease Rating Scale (total score, as well as parts II and III individually), the Berg Balance Scale, and the 30 m walking time. When compared to the control group, the bee venom acupuncture group experienced significantly greater improvement on the Unified Parkinson's Disease Rating Scale. In the acupuncture group, the Unified Parkinson's Disease Rating Scale (part III and total scores) and the Beck Depression Inventory showed significant improvement. The control group showed no significant changes in any outcome after 8 weeks. In this pilot study, both acupuncture and bee venom acupuncture showed promising results as adjuvant therapies for Parkinson's disease.
本研究旨在探讨针灸和蜂毒针灸作为特发性帕金森病辅助治疗的效果。我们招募了 43 名特发性帕金森病患者，他们已经稳定服用抗帕金森病药物至少 1 个月。他们被随机分为 3 组：针灸组、蜂毒针灸组和对照组。所有参与者均使用统一帕金森病评定量表、帕金森病生活质量问卷、贝克抑郁量表、伯格平衡量表和行走 30 米所需的时间和步数进行评估。治疗组每周接受 2 次 10 个穴位的刺激，共 8 周。初始评估在治疗结束时重复。对照组未接受任何治疗。蜂毒针灸组在统一帕金森病评定量表（总分以及第二和第三部分）、伯格平衡量表和 30 米行走时间上均有显著改善。与对照组相比，蜂毒针灸组在统一帕金森病评定量表上的改善更为显著。在针灸组中，统一帕金森病评定量表（第三部分和总分）和贝克抑郁量表均有显著改善。对照组在 8 周后任何结果均无显著变化。在这项初步研究中，针灸和蜂毒针灸均显示出作为帕金森病辅助治疗的潜力。
