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巨细胞动脉炎:全科医疗中的诊断、处方和监测。

Polymyalgia rheumatica: diagnosis, prescribing, and monitoring in general practice.

机构信息

Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffordshire.

出版信息

Br J Gen Pract. 2013 May;63(610):e361-6. doi: 10.3399/bjgp13X667231.

Abstract

BACKGROUND

Polymyalgia rheumatica (PMR) is a common rheumatological disorder of older patients. The majority of UK patients are diagnosed and managed exclusively in general practice. In primary care, it has been shown that there is wide variation in practice, and established diagnostic criteria are infrequently used.

AIM

This study aims to investigate the diagnostic processes, management, and monitoring of patients with PMR in UK primary care.

DESIGN AND SETTING

This is a retrospective cohort study set in primary care.

METHOD

Data were extracted from two interlinked primary care databases from north Staffordshire. Patients with PMR were identified using Read Codes and the relevant investigation, prescription, and consultation data were extracted and reviewed.

RESULTS

Three hundred and four patients' records were analysed. Documentation of symptoms leading to a diagnosis of PMR was found in 248 records (81.6%). A documented process of exclusion of relevant differential diagnoses was demonstrated in 68 (22.4%) patients. The mean initial dose of prednisolone was 21.5 mg. Referral to specialist care was made for 135 (44.4%) patients. Gastric prophylaxis was prescribed in 85 (28.0%) cases. Osteoporosis prophylaxis was prescribed to 183 patients (60.2%); 12 patients (3.9%) developed osteoporosis and 56 (18.4%) developed gastric symptoms that led to GP consultation.

CONCLUSION

The management of PMR in general practice could be optimised. Identified areas for improvement include clear documentation of a process of exclusion of other diagnoses, and prophylaxis for potential treatment complications, including osteoporosis and gastric symptoms.

摘要

背景

巨细胞动脉炎(PMR)是一种常见的老年患者风湿性疾病。大多数英国患者仅在全科医生处被诊断和管理。在初级保健中,已经表明实践中存在广泛的差异,并且很少使用既定的诊断标准。

目的

本研究旨在调查英国初级保健中 PMR 患者的诊断过程、管理和监测。

设计和设置

这是一项在初级保健中进行的回顾性队列研究。

方法

数据从北斯塔福德郡的两个相互关联的初级保健数据库中提取。使用 Read 代码识别出 PMR 患者,提取并审查相关的检查、处方和咨询数据。

结果

分析了 304 名患者的记录。在 248 份记录(81.6%)中发现了导致 PMR 诊断的症状记录。在 68 名(22.4%)患者中证明了排除相关鉴别诊断的过程记录。初始泼尼松龙剂量的平均值为 21.5mg。为 135 名(44.4%)患者转诊至专科治疗。为 85 名(28.0%)患者开具了胃保护剂。为 183 名患者(60.2%)开具了骨质疏松症预防药物;12 名患者(3.9%)发生骨质疏松症,56 名患者(18.4%)出现胃部症状,导致全科医生咨询。

结论

在一般实践中,PMR 的管理可以得到优化。需要改进的领域包括明确记录排除其他诊断的过程,以及预防潜在的治疗并发症,包括骨质疏松症和胃部症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45c3/3635583/530cd67973fa/bjgp-may2013-63-610-e361-1.jpg

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