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刺蒺藜皂苷治疗冠心病心绞痛406例

[406 cases of angina pectoris in coronary heart disease treated with saponin of Tribulus terrestris].

作者信息

Wang B, Ma L, Liu T

机构信息

Research Unit of Cardiovascular Disease, Jilin Medical College.

出版信息

Zhong Xi Yi Jie He Za Zhi. 1990 Feb;10(2):85-7, 68.

PMID:2364467
Abstract

Coronary heart disease (CHD) was treated with saponin of Tribulus terrestris. According to 406 cases of clinical observation and a cross test (67 cases treated with Yufen Ningxin Pian as control), the results showed that the total efficacious rate of remission angina pectoris was 82.3%. It was higher than the control group with a total effective rate of 67.2% (P less than 0.05). The total effective rate of ECG improvement (52.7%) was even higher than that of the control group (35.8%). It is shown that saponin of Tribulus terrestris has the action of dilating coronary artery and improving coronary circulation, and thus has better effects on improving ECG of myocardial ischemia. If taken for a long time, it has no adverse reaction on blood system and hepatic and renal functions. Neither does it have side effects. It is one of the ideal medicines to treat angina pectoris.

摘要

用刺蒺藜皂苷治疗冠心病。通过406例临床观察及交叉试验(67例用愈风宁心片作对照),结果表明,缓解心绞痛的总有效率为82.3%。高于对照组的总有效率67.2%(P<0.05)。心电图改善的总有效率(52.7%)甚至高于对照组(35.8%)。表明刺蒺藜皂苷有扩张冠状动脉、改善冠脉循环的作用,因而对改善心肌缺血心电图有较好效果。长期服用对血液系统及肝肾功能无不良反应,也无副作用。是治疗心绞痛的理想药物之一。

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