UCNS Certified Headache Medicine, ABPN Certified Adult Neurology, Belmont, MI, USA.
Curr Pain Headache Rep. 2013 Jun;17(6):336. doi: 10.1007/s11916-013-0336-9.
Burning mouth syndrome (BMS) is a complex chronic disorder of orofacial sensation that is challenging in both diagnosis and treatment. The diagnosis of BMS is primarily one of exclusion, and recently classification of the disorder has been challenged. Although the exact pathophysiology of primary BMS is unknown, there has been a growing body of work to provide insight into the pathogenesis of the disorder over the past few years. Pharmacological treatments recently reported to have some success in BMS include anxiolytics, anticonvulsants, antidepressants, atypical antipsychotics, histamine receptor antagonist, and dopamine agonists. In addition, other therapies and treatments are being considered. This paper reports many of the most recent data related to BMS and its classification, diagnosis, impact on quality of life, pathophysiology, co-morbidities, and pharmacological and non-pharmacological treatments.
灼口综合征（BMS）是一种复杂的慢性口腔感觉障碍，在诊断和治疗方面都具有挑战性。BMS 的诊断主要是排他性的，最近对该疾病的分类也受到了挑战。尽管原发性 BMS 的确切病理生理学尚不清楚，但在过去几年中，已经有越来越多的工作旨在深入了解该疾病的发病机制。最近报道在 BMS 中具有一定疗效的药物治疗包括抗焦虑药、抗惊厥药、抗抑郁药、非典型抗精神病药、组胺受体拮抗剂和多巴胺激动剂。此外，还在考虑其他治疗方法。本文报告了许多与 BMS 及其分类、诊断、对生活质量的影响、病理生理学、合并症以及药物和非药物治疗相关的最新数据。
